RISK FACTORS AND FETOMATERNAL OUTCOME IN PREGNANT WOMEN WITH PERIPARTUM CARDIOMYOPATHY
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Keywords
Risk factors, Fetomaternal Outcome, Pregnant Women, Peripartum Cardiomyopathy
Abstract
Objective: The aim of the study was to determine the Risk factors and Fetomaternal Outcome in Pregnant Women with Peripartum Cardiomyopathy
Methodology: The current cross sectional study was carried out from December 2022 to May 2023 at the Department of Cardiology Khalifa Gul Nawaz Teaching Hospital MTI Bannu and Peshawar institute of cardiology Peshawar after taking approval from the ethical committee of the institute. After obtaining informed permission, women with peripartum cardiomyopathy diagnoses, regardless of age or parity, were included. Women having a history of anemia or valvular heart disease were excluded from the study.SPSS version 20 was uses for the data analysis. For quantitative variables mean and standard deviation were computed. For qualitative variables percentages and frequency were evaluated.
Results: In the current study a total of 66 pregnant women diagnosed with peripartum cardiomyopathy were enrolled. The most prevalent age group of the study participants were from 31 to 35 years (45.45%). Majority of the individuals 41(62.12%) offered at <37 weeks (preterm) gestation. the frequency of primigravidain were (18.18%). Almost 1/3 of the participants 24(36.36) had two to four children. A parity of greater than 4 was evaluated in 30(45.45%) women. 49(74.2%) individuals had Pre-eclampsia while (27.27%) had chronic hypertension. (93.93%) individuals had singleton pregnancy and twin pregnancy was detected in 4(6.0%) participants. A total of (75.7%) women had done cesarean section due to heart failure and pulmonary edema and 16(24.2%) had spontaneous vaginal delivery. 54(81.8%) babies were born alive and 12(18.18% were intrauterine death. Due to various factors there were 16(24.24%) maternal death occurred.
Conclusion: Peripartum cardiomyopathy is a sporadic but severe disorder of unidentified origin that affects women of childbearing age. Risk factors evaluated were advanced age, Pre-eclampsia and chronic hypertension. 24% maternal and 18.18 % fetus death explored in the current study.
References
2. Mielniczuk LM, Williams K, Davis DR, Tang AS, Lemery R, Green MS, et al. Frequency of peripartum cardiomyopathy. Am J Cardiol. 2006; 97:1765-8.
3. Hasan JA, Qureshi A, Ramejo BB, Kamran A. Peripartum cardiomyopathy characteristics and outcome in a tertiarycare hospital. J Pak Med Assoc. 2010; 60:377-80.
4. Bhandary A, Rambhatla T, Coplan N, Kronzon I. Peripartum cardiomyopathy: A contemporary review. J Clin Prev Cardiol. 2018;7:54-9.
5. Gunderson EP, Croen LA, Chiang V, Yoshida CK, Walton D, Go AS. Epidemiology of peripartum cardiomyopathy: incidence, predictors, and outcomes. Obstet Gynecol. 2011; 118:583-91.
6. Kolte D, Khera S, Aronow WS, Palaniswamy C, Mujib M, et al. Temporal trends in incidence and outcomes of peripartum cardiomyopathy in the United States: a nationwide population- based study. J Am Heart Assoc. 2014;3:-001056.
7. Sliwa K, Hilfiker-Kleiner D, Petrie MC, Mebazaa A, Pieske B, Buchmann E, et al; Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy. Current state of knowledge on aetiology, diagnosis, , and therapy of peripartum cardiomyopathy: a position statement from the Heart Failure Association of the European Society of Cardiology Working Group on Peripartum Cardiomyopathy. Eur J Heart Fail. 2010; 12:767-78.
8. Bhalerao A, Garg R. Pregnancy outcome in peripartum cardiomyopathy. Inter J Obstet Gynaecol Res. 2016; 8:38-49.
9. Bhakta P, Biswas BK, Banerjee B. Peripartum cardiomyopathy: review of the literature. Yonsei Med J. 2007; 48:731-47.
10. Fett JD, Christie LG, Carraway RD, Murphy JG. Five-year prospective study of the incidence and prognosis of peripartum cardiomyopathy at a single institution. Mayo Clin Proc. 2005; 80:602-6.
11. Pandit V, Shetty S, Kumar A, Sagir A. Incidence and outcome of peripartum cardiomyopathy from a tertiary hospital in South India. Tropical doctor. 2009; 39:168-9
12. Isezuo SA, Abubakar SA. Epidemiologic profile of peripartum cardiomyopathy in a tertiary care hospital. Ethn Dis. 2007; 17:228-33.
13. Ahmed I, Masroor M, Qamar R, Hashim KA, Sattar A, Imran K, et al. Risk factors associated with peripartum cardiomyopathy. Pak Heart J. 2003; 36:4-8.
14. Muhammad Z, Nadeem MA, Hussain I. Peripartum cardiomyopathy presenting to cardiology department of Mayo Hospital, Lahore. Ann King Edward Med Uni. 2006; 12:212-4.
15. Sharieff S, Zaman KS. Identification of risk factors and demographic features of patients with peripartum cardiomyopathy. J Pak Med Assoc. 2003; 53:297-300.
16. WHO Expert Consultation. Appropriate bodymass index for Asian populations and its implications for policy and intervention strategies. Lancet. 2004; 363(9403):157-63.
17. Memon NA, Kadir S, Memon AG. Risk Factors associated with peripartum cardiomyopathy. J Liaquat Uni Med Health Sci. 2005;20;119-22.
18. Laghari AH, Khan AH, Kazmi KA. Peripartum cardiomyopathy: ten years’ experience at a tertiary care hospital in Pakistan. BMC Res Notes. 2013;6:1-4.
19. Samonte VI, Ngalob QG, Mata GD, Aherrera JA, Reyes E, Punzalan FE. Clinical and echocardiographic profile and outcomes of peripartum cardiomyopathy: The Philippine General Hospital experience. Heart Asia. 2013;5:245-9.
20. Vani YJ, Vemu A. Maternal and fetal outcome in women with cardiac disease- a retrospective study in tertiary care center. IOSR J Dental Med Sci. 2017; 16:50-3
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Khalid Naseem Khan
Cardiologist Khalifa Gul Nawaz Teaching Hospital MTI Bannu
Hira Amin
Gynecologist DHQ Hospital Lakki Marwat
Rizwan Ullah
Cardiologist Peshawar institute of cardiology Peshawar
Ayesha Fareed
4th year student Bannu Medical College Bannu
Aimen Farid
4th year student Bannu Medical College Bannu
Aitsam Ullah Shah
Medical Officer Khalifa Gul Nawaz Teaching Hospital MTI Bannu