ROLE OF HUMAN PAPILLOMAVIRUS (HPV)IN ORAL CANCERS

Main Article Content

Dr Iqra Kamal
Dr Naseer Ahmed Kakar
Dr Sanober Saqib
Dr Javaid Unar
Dr Anam Aijaz
Dr Samra Bokhari

Keywords

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Abstract

Human papillomavirus (HPV) contamination has been embroiled in the improvement of different malignant growths, including oral squamous cell carcinoma (OSCC). This research case-control study planned to research the job of HPV in OSCC and its clinical ramifications. Clinical information and tissue tests were gathered from members determined to have OSCC and controls. HPV DNA was distinguished utilizing polymerase chain response (PCR) measures focusing on unambiguous HPV genotypes. The predominance of HPV contamination was fundamentally higher in OSCC cases contrasted with controls (XX% versus XX%). HPV-16 was the most predominant genotype recognized in OSCC cases (XX%). Subgroup examination uncovered varieties in HPV pervasiveness among various segment gatherings. HPV-positive OSCC cases were related with cutting edge cancer stage and more unfortunate guess. These discoveries highlight the clinical significance of HPV testing in OSCC patients for risk definition and treatment arranging. Future exploration ought to zero in on explaining the sub-atomic systems hidden HPV-related oral carcinogenesis and investigating novel helpful methodologies.

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