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Tasnia Habib
Lubna Khondker
Humayan Kabir
Mukhlachur Rahman
Mst. Dil Afroz Bhuiyan
Sabequn Nahar-E-Farzana
Mozammal Hossain


Carbon dioxide laser, Oral lichen planus, Oral mucocutaneous lesion.


The purpose of this review article was to determine whether carbon dioxide (CO2) laser treatment is beneficial for oral lichen planus and to provide the most recent, comprehensive information that includes any new developments. This systematic review was completed from March 2022 to December 2023 at Udayan Dental College and Hospital, Rajshahi, Bangladesh. Search categories were specifically followed to databases like PubMed, PubMed Central, Cochrane, Medline, Embase, Cross Ref and in Google Scholar. Articles published between 2014 and 2023 were reviewed using MeSH (Medical Subject Headings) terms for example oral lichen planus, carbon dioxide laser, and oral premalignant condition. Total 90 articles were selected to review, however following analysis, only ten articles met the predetermined inclusion and exclusion criteria. Among these publications, 2 retrospective studies, 1 prospective study, 2 clinical trials, 1 comparative study, 1 non-randomized controlled trial (NRCT), 1 scoping review, 1 single arm intervention study, and 1 case report were reviewed. This systematic study concludes the carbon dioxide laser is a very proficient tool for treating widespread lesions and is effective in the management of oral lichen planus. Recurrence frequency of the lesion was fewer after absorbed at a preliminary stage by the application of carbon dioxide laser.

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