OVERVIEW OF SYSTEMIC LUPUS ERYTHEMATOSUS RISK FACTORS AND RELATED COMPLICATIONS
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Keywords
Systemic lupus erythematosus (SLE), Etiology, Pathophysiology, Flare, Complications
Abstract
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease where the immune system attacks the body's cells and tissues, causing inflammation and tissue damage. SLE presents clinically in a diverse manner, impacting various organs such as the heart, joints, skin, lungs, kidneys, and nervous system. The production of autoantibodies, especially antinuclear and anti-DNA antibodies, is linked to SLE and its symptoms may vary among patients, with common signs including rash, arthritis, and fatigue. The disease's development involves genetic, epigenetic, and environmental elements, influencing abnormal B- and T-cell activity.
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Abdullah Mohammad Albihani
King Salman Bin Abdulaziz Medical City – Madinah – Saudi Arabia
Mahmood Yassin Alattas
King Salman Bin Abdulaziz Medical City – Madinah – Saudi Arabia
Alaa Kamaladdin Ahmed
King Salman Bin Abdulaziz Medical City – Madinah – Saudi Arabia
Yarob Yousef Khesherim
King Salman Bin Abdulaziz Medical City – Madinah – Saudi Arabia
Murtadha Ahmed Ibrahem Alkhalaf
Al Jafer General Hospital - Al Hasa – Saudi Arabia
Alaa Salamah Aljohani
Al Meqat Hospital – Madinah – Saudi Arabia
Mohammed Saeed Alqahtani
Saudi Red Crescent Authority – Riyadh – Saudi Arabia
Matar Dibas Alotaibi
Saudi Red Crescent Authority – Riyadh – Saudi Arabia
Abdul Rahman Abdullah Al-Sahli
Saudi Red Crescent Authority – Riyadh – Saudi Arabia
Ahmed Salman Alsharef
King Salman Bin Abdulaziz Medical City – Madinah – Saudi Arabia
Hamad Abdulrahman Algaeed
King Abdullah Bin Abdulaziz University Hospital – Riyadh – Saudi Arabia
Danah Mohammed Alsibai
King Abdullah Bin Abdulaziz University Hospital – Riyadh – Saudi Arabia
Mujahid Salih Aldhaif
King Abdullah Bin Abdulaziz University Hospital – Riyadh – Saudi Arabia