CUTANEOUS MANIFESTATIONS OF SYSTEMIC DISEASES: A RETROSPECTIVE STUDY ANALYZED STUDY

Abstract

Objectives: This study investigated the prevalence and characteristics of cutaneous manifestations in systemic diseases, identified common skin involvement patterns, and highlighted the importance of dermatological evaluation in the diagnosis and management of underlying systemic conditions.

Study Design: A retrospective study.

Methods: This retrospective study analyzed 100 patient records from the Department of Dermatology, PIMS Hospital, Islamabad, between January 2021 and January 2022. Data on patient demographics, including gender distribution (35% male, 65% female) and age (20-45 years), were collected. Cutaneous manifestations were categorized based on clinical presentation and associated systemic diseases. Diagnostic approaches were documented, including clinical evaluation, laboratory investigations, and biopsy. The study aimed to identify common cutaneous manifestations and their association with underlying systemic diseases, highlighting the importance of dermatological evaluation in diagnosing systemic conditions.

Results: Out of 100 patients gender wise n-35 (355) male and n-65(65%) female age distribution of patients age group 20-25 n-15(15%),26-30 n-35(35%),31-35 n-15(15%),36-40 n-15(15%),41-45 n-20(20%)table no 3 show Table 3 Common Cutaneous Manifestations Manifestation Number of Patients Rashes and Eruptions n-25(25%), Pigmentary Changesn-15(15%), Nail Abnormalitiesn-20 (20%) Ulcerations and Lesions n-20(20%), Other (Specify)n-20(20%) Table 4 shows Underlying Systemic Diseases Associated with Cutaneous Manifestations Systemic Disease Number of Patients Lupus Erythematosusn-45(45%) Vasculitisn-15(15%), Diabetes Mellitusn-25(25%), Thyroid Dysfunctionn-5(5%), Psoriasis n-5(5%), Connective Tissue Disordersn-5(5%) Other (Specify)n-5 (5%) table number 5 shows  Diagnostic Approach for Patients with Cutaneous ManifestationsClinical Evaluation     n-35(35%), Laboratory Investigationsn-15(15%), Imaging Studiesn-20(20%), Biopsyn-25(25%), Other (Specify)n-15(15%)

Conclusion: A retrospective analysis of 100 patient records from the Department of Dermatology, PIMS Hospital, Islamabad, was conducted between January 2021 and January 2022. Data on patient demographics, including gender distribution (35% male, 65% female) and age (20-45 years), were collected. Cutaneous manifestations were categorized based on clinical presentation and associated systemic diseases. Diagnostic approaches were documented, including clinical evaluation, laboratory investigations, and biopsy.