THE FREQUENCY OF SKIN AND SOFT TISSUE INFECTIONS IN PATIENTS WITH DIABETES AT A PIMS HOSPITAL IN ISLAMABAD

Main Article Content

Faryal Afridi
Sadia Anwar
Mehwish Gul
Maria Saleem

Keywords

Diabetes, Infections, frequency, PIMS Hospital

Abstract

Objectives: To determine the  frequency  of skin and soft tissue infections in diabetic patients at PIMS Hospital, Islamabad, from January 2022 to January 2023, and assess associated factors.


METHODS: The skin department of PIMS Hospital in Islamabad performed the present cross-sectional investigation. This research was conducted from January 2022 to January 2023.  The research population will consist of all diabetic patients admitted to this hospital. The information was obtained via the use of a pretested semi-structured interview questionnaire with both closed- and open-ended questions. A face-to-face interview was conducted using the questionnaire.  Respondents received thorough explanations in their own language for each question.Analysis using statistics: The statistical package for social sciences (SPSS) 18.0 vision was used to examine the data.  Chi-square (2), logistic regression, frequency and percentage ratios, and other techniques were used to examine the collected data.


RESULTS :There were 223 participants in all for this research.  Of the total respondents, 108 (49.2%) and 115 (51.8%) were men and women, respectively. Participants in the study ranged in age from 16 to over 45. Of these, the respondents with the highest percentage were between the ages of 35 and 41 (20.65%), 42 (20.05%), 24-31 (14.5%), > 38 (12.8%), 20–24 years old 28 (13.05%), 15–21 years old 12 (11.2%), and 11–16 years old 10 (09.00%).    The majority of responders were from rural regions, whereas the minority were from metropolitan areas.  206 (89.95%) of the 229 females were afflicted with soft and tissue infection, whereas 90 (83.45%) of the 108 men overall had the illness.


Conclusion: The study conducted at PIMS Hospital in Islamabad revealed a substantial  frequency  of skin and soft tissue infections among diabetic patients. Female patients exhibited a higher susceptibility. Further investigations are needed to identify contributing factors and develop targeted interventions to mitigate these infections and improve diabetic care.

Abstract 103 | PDF Downloads 38

References

1. International Diabetes Federation (IDF). (2019). IDF Diabetes Atlas, 9th Edition. Retrieved from https://diabetesatlas.org
2. American Diabetes Association. (2022). Standards of Medical Care in Diabetes—2022. Diabetes Care, 45(Supplement_1). https://doi.org/10.2337/dc22-S001
3. Singh, N., Armstrong, D. G., & Lipsky, B. A. (2018). Preventing foot ulcers in patients with diabetes. JAMA, 320(13), 1328-1329. https://doi.org/10.1001/jama.2018.12488
4. World Health Organization. Global report on diabetes. 2016. Available at: https://www.who.int/publications/i/item/9789241565257. Accessed August 3, 2020.
5. Risk of infection in type 1 and type 2 diabetes compared with the general population: a matched cohort study. Diabetes Care. 2018; 41: 513-521
6. Skin and soft tissue infections and associated complications among commercially insured patients aged 0-64 years with and without diabetes in the U.S. PLoS One. 2013; 8: e60057
7. Diabetes mellitus and infection: an evaluation of hospital utilization and management costs in the United States. J Diabetes Complications. 2015; 29: 192-195
8. The role of diabetes mellitus in the treatment of skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: results from three randomized controlled trials.Int J Infect Dis. 2011; 15: e140-e146
9. Factors associated with readmission and mortality in adult patients with skin and soft tissue infections. Int J Dermatol. 2019; 58: 916-924
10. Risk factors for foot infections in individuals with diabetes.Diabetes Care. 2006; 29: 1288-1293
11. Disparities in outcomes of patients admitted with diabetic foot infections. PLoS One. 2019; 14: e0211481
12. The effects of type 2 diabetes mellitus on organ metabolism and the immune system. Front Immunol. 2020; 11: 1582
13. A proposed new classification of skin and soft tissue infections modeled on the subset of diabetic foot infection.Open Forum Infect Dis. 2017; 4: ofw255
14. The impact of gram-negative bacilli in bacteremic skin and soft tissue infections among patients with diabetes. Diabetes Care. 2019; 42: e110-e112
15. Predictors of methicillin-resistant Staphylococcus aureus colonization at hospital admission. Am J Infect Control. 2013; 41: 1043-1047
16. Understanding the microbiome of diabetic foot osteomyelitis: insights from molecular and microscopic approaches. Clin Microbiol Infect. 2019; 25: 332-339
17. Bacteriology of moderate-to-severe diabetic foot infections and in vitro activity of antimicrobial agents. J Clin Microbiol. 2007; 45: 2819-2828