THROMBOCYTOPENIA AND ITS SIGNIFICANCE IN TOXEMIA OF PREGNANCY.
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Keywords
Pregnancy Induced Hypertension (PIH), Preeclampsia, Eclampsia, Platelet count, Hematological marker
Abstract
Toxemia of pregnancy is a scantily understood condition of human pregnancy, which can influence multiple organs and is a foremost reason of maternal mortality worldwide. There is also indication that preeclampsia is usually related with placental hypoxia and endothelial dysfunction. Many researchers gave their efforts to recognize the exclusive screening test that would predict the risk of developing preeclampsia before the typical symptoms appear. There are number of studies which suggest platelet may play a chief role in the etiopathogenesis of preeclampsia. The present study done in 170 pregnant mothers divided into four groups.40 cases of mild preeclampsia, 40 cases of severe preeclampsia,40 cases of Eclampsia and 50 cases of control (Normotensive) pregnant women admitted in Department of Obs and Gynae, Rama Medical College, hospital and research centre. There was significant difference between platelet counts of eclampsia (<0.0001), severe preeclampsia (0.0002), mild preeclampsia(P=0.0004) when compared to control group. Platelet count may be considered as an early, economical and quick method to estimate the severity of PIH cases. It can also be a useful screening test for early recognition and to assess the prognosis of the disease and outcome in pregnant women.
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Dr.T. Praveen
Associate professor, Department of Anatomy, Ayaan institute of medical sciences, Moinabad, R.R.Dist, Telanagana
Dr. Nelapati Swetha Vinela
Assistant. Professor, Department of Bio chemistry, Ayaan Institute of medical sciences, Moinabad, R.R. Dist, Telanagana
Dr. Kirankumar P
Associate professor, Department of Anatomy, Chalmeda Ananda Rao Institute of medical sciences, Bommakal, Karimnagar, Telangana