AN ASSESSMENT OF DRUG PRESCRIPTION PATTERN AND THEIR SAFETY CONCERN AMONG PATIENT TREATED WITH ANTIDIABETIC DRUGS IN TERTIARY CARE TEACHING HOSPITALS
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Keywords
Antidiabetic Drugs, ADRs, B/R ration, Drug Safety
Abstract
Introduction: In India, Diabetes Mellitus is probably becoming a pandemic. India's diabetes population is predicted to grow from approximately 69.2 million in 2015 to 123.5 million in 2040. It can be treated by various types of Antidiabetic Drugs that has not only beneficial effect; it also causes adverse drug reactions.
Method: This was a prospective and observational study conducted in Department of Pharmacology, Santosh Medical College in Collaboration with Department of Medicine, Muzaffarnagar Medical College (MMC), Muzaffarnagar, UP. A total of 109 Diabetic patients treated with Antidiabetic drugs presented in Medicine OPD of MMC Hospital were included and data were assessed for rational prescription as per WHO prescription indicators and also for drug safety concern.
Results: Maximum number of drug prescribed in this study was Biguanide derivative and its FDCs Sulphonylureas + Biguanide + Thiazolidinedione showed less number of ADRs (B/R, 0.13) is a safe drug either alone or with FDCs.
Conclusion: ADRs could be minimized with rational prescription and FDCs
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Lalendra Yadav
Assistant Professor, Department of Pharmacology, Government Medical College, Budaun, Uttar Pradesh
Shaktibala Dutta
Professor & HOD, Department of Pharmacology, Graphic Era Institute of Medical
Science (GEIMS), Dehradun, Uttrakhand (UK).
Jyotsna Sharma
Professor & HOD, Department Pharmacology (GS Medical College, Pilkhuwa, Hapur), UP.
Rajani Rai Sukla
Assistant Professor, Department of Pharmacology, Santosh Medical College and Hospital, Ghaziabad, Uttar Pradesh.
Ila Pahwa
Professor of Medicine, Muzaffarnagar Medical College, Muzaffarnagar, Uttar Pradesh.