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Muhammad Amin
Tariq Nawaz
Hassan Ali
Wasim Sajjad
Sadam Hussain


Prosthetic valve thrombosis, clinical profile, treatment


Background: Prosthetic valve thrombosis is one of the most well-known life-threatening complications after valve replacement surgery. A poor antithrombotic status causes this thrombotic condition.

Objective: The purpose of this study to examine how prosthetic valve thrombosis was treated at our institute. Furthermore clinical characteristics of the patients were also assessed.

Methodology: This observational study was conducted at the cardiology department of Lady reading hospital Peshawar. The study covered 20 patients who consulted the cardiology unit from October 2022 to October 2023. The patients who were recently diagnosed with PV thrombosis were selected. Each patient's clinical characteristics and demographic profile were noted. In-hospital results were also examined. All the data was analyzed by using SPSS 23.

Results: This observational study was conducted on 20 patients. The majority were female patients (55%) in this study. Fluoroscopy was used to confirm the diagnosis further. The patients with PV thrombosis ranged in age from 12 to 70, with an average age of 36 years. After one week of symptoms, 90% of patients were allowed to admission in the hospital. Ninety percent of the patients reported difficulty breathing and other symptoms. Thrombolysis was the most usually utilized treatment, administered to 92% of the patients.

Conclusion: A significant mortality rate is linked to PV thrombosis in a clinical emergency. Poor anticoagulation therapy compliance is a consequence of low socioeconomic levels. Daily updates to the PV thrombosis treatment recommendations need proper disease management to improve medication compliance. The use of thrombolysis in the treatment of prosthetic valve thrombosis is thought to be beneficial.

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