PERIODONTAL DISEASE AS A POTENTIAL RISK FACTOR FOR NEURODEGENERATIVE DISEASE

Dr Sana Mukhtar; Dr Sakina Qazi; Dr. Mirza Shayan Baig; Dr Joham Gul; Dr Nida Gull; Dr Muhammad Umair

doi:10.53555/jptcp.v30i18.3521

Dr Sana Mukhtar
Dr Sakina Qazi
Dr. Mirza Shayan Baig
Dr Joham Gul
Dr Nida Gull
Dr Muhammad Umair

Keywords

Oral-Systemic Health, Age Moderation, Statistical Correlation, Public Health Recommendations, Biological Mechanisms, Neurodegenerative Disorders, Periodontal Disease, Chronic Inflammation, Cross-Sectional Analysis, Risk Assessment

Abstract

Objective: The study explores the correlation among periodontal disease and neurodegenerative disorders, which involve inflammatory processes. The global neurodegenerative disease increase underlines the need to identify potential contributing factors.

Methods: A cross-sectional analysis was conducted on participants aged 40 and above. Both dental examinations for periodontal disease and neurological evaluations for symptoms of neurodegenerative diseases were performed. Statistical analyses were conducted using SPSS software, employing chi-square and logistic regression models.

Findings: The analysis demonstrated a significant correlation between periodontal disease and symptoms of neurodegenerative disorders. Chi-square tests revealed a notable interaction with age as a moderating variable. Our findings align with existing literature that points to chronic inflammation as a shared component in periodontal and neurodegenerative diseases. The connection is further supported by oral pathogens in brain tissue samples from Alzheimer's patients.

Conclusions: The review proposes that unfortunate oral well-being might be a gamble factor for neurodegenerative sicknesses. Including oral health in broader public health strategies, further investigation into underlying biological mechanisms, and regular dental checkups are among the recommendations.

Abstract 229 | PDF Downloads 104

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Published

Nov 25, 2023

DOI https://doi.org/10.53555/jptcp.v30i18.3521

How to Cite

Dr Sana Mukhtar, Dr Sakina Qazi, Dr. Mirza Shayan Baig, Dr Joham Gul, Dr Nida Gull, & Dr Muhammad Umair. (2023). PERIODONTAL DISEASE AS A POTENTIAL RISK FACTOR FOR NEURODEGENERATIVE DISEASE. Journal of Population Therapeutics and Clinical Pharmacology, 30(18), 2727–2737. https://doi.org/10.53555/jptcp.v30i18.3521

Issue

Vol. 30 No. 18 (2023): JPTCP

Section

Articles

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.

Author Biographies

Dr Sana Mukhtar

Senior Registrar, Foundation University College of Dentistry Islamabad

Dr Sakina Qazi

Assistant Professor, HOD Periodontology, University Medical and Dental college Faisalabad.

Dr. Mirza Shayan Baig

BDS, MCPS, MDS (R), Islamic International Dental Hospital. Riphah International University, Islamabad.

Dr Joham Gul

Department of Oral and Maxillofacial Surgery, Karachi Medical and Dental College, Abbasi Shaheed General Hospital, Karachi.

Dr Nida Gull

General Dentist.

Dr Muhammad Umair

Assistant Professor/ HOD, Department of Oral Medicine, Foundation University, College of Dentistry, Islamabad

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