ADVANCEMENTS IN DRUG DELIVERY FOR CHRONIC INFLAMMATORY DISEASES: RECENT APPROACHES AND STRATEGIES

Main Article Content

Arushi Saloki
Taranjeet Kukreja
Swarnlata Saraf

Keywords

Chronic inflammation, Inflammatory disease, Drug delivery system, Anti-inflammatory drugs, Phytochemicals

Abstract

The inflammatory process constitutes one of the organism's most fundamental and obvious defense mechanisms. Inflammation is a physiological response of the immunity caused by pathogens, toxic compounds, and damaged cells capable of causing chronic and acute inflammation. This may cause tissue damage or disease. Several therapies are currently available to reduce symptoms and prevent disease progression. However, more efficient treatments are required due to the severe side effects of current therapies, particularly when used long-term. With several nano-formulations, the delivery of drug systems has proven clinically important. In the present paper, we have reviewed chronic inflammatory diseases based on their inflammatory response mechanism. Also focused on recent approaches and targets for treating rheumatoid arthritis is one example of a chronic inflammatory condition. Moreover, for the intervention of inflammation, the current scenario of nano-formulated anti-inflammatory agents from conventional drugs and phytochemical drugs is described in the paper.

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