NLC BASED TOPICAL NANO FORMULATIONS FOR THE MANAGEMENT OF ATOPIC DERMATITIS: AN UPDATED REVIEW
Main Article Content
Keywords
Atopic dermatitis, Nanostructure lipid carriers, Drug transport, Topical therapy, Inflammation, Rat model
Abstract
Atopic dermatitis (AD) affects children and adolescents worldwide. Novel drug delivery mechanisms are needed for conventional anti-inflammatory drugs to work well. This study proposes employing Nano formulation-Nanostructure Lipid Carriers (NLCs) loaded drug to treat Atopic Dermatitis and provides current and future prospects as well. A detailed literature analysis of Atopic Dermatitis, drug delivery methods, NLCs, and the therapeutic effects of drug therapies starts the investigation. Previous research on Atopic Dermatitis drug delivery devices, notably NLCs, emphasises the potential advantages of this new technique. The NLC gel formulation review strategy includes selecting and purchasing high-quality medicines and excipients. Optimised methods produce drug-loaded NLC particles. NLC gel therapeutic effectiveness is tested in a rat model of AD. The study might cure AD. NLCs loaded with drug may enhance therapeutic effects. NLC gel's deep skin penetration and continuous drug release make it a viable AD treatment. This discovery leads to successful and unique drug delivery method for atopic dermatitis therapy, resolving the limits of traditional medications and improving patient care. The goal of this review is to give readers a better understanding of AD and the problems with current AD treatments. The review of present and emerging nanomedicine NLCs for the successful treatment of AD remains the main focus. The review highlights the advantages of nanostructure lipid carriers in addressing problems with current products and their potential future effects.
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Aug 10, 2023
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Taranjeet Kukreja, & Swarnlata Saraf. (2023). NLC BASED TOPICAL NANO FORMULATIONS FOR THE MANAGEMENT OF ATOPIC DERMATITIS: AN UPDATED REVIEW. Journal of Population Therapeutics and Clinical Pharmacology, 30(3), 708–720. https://doi.org/10.53555/jptcp.v30i3.2501
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Author Biographies
Taranjeet Kukreja
Department of Pharmacy, University Institute of Pharmacy, Pandit Ravishankar Shukla University, Raipur – 492001, Chhattisgarh, India
Swarnlata Saraf
Department of Pharmacy, University Institute of Pharmacy, Pandit Ravishankar Shukla University, Raipur – 492001, Chhattisgarh, India