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Due to obvious ethical issues of experimenting drugs during fetal development, women and their unborn babies are commonly excluded from drug trials. As a result, these two groups of patients are commonly orphaned from the revolution in drug therapy witnessed in the last generation.
2. Heikkinen T, Ekblad U, Palo P, Laine K. Pharmacokinetics of fluoxetine and norfluoxetine in pregnancy and lactation. Clin Pharmacol Ther 2003; 73: 330-7.
3. Bonari L, Bennett H, Einarson A, Koren G. Risks of untreated depression during pregnancy. Can Fam Physician 2004; 50: 37- 9.
4. Koren G. Maternal- Fetal Toxicology; A Clinician’s Guide. Marcel Dekker, NY, 3rd edition, 2001.
5. Elliott BD, Schenker S, Langer O, Johnson R, Prihoda T. Comparative placental transport of oral hypoglycemic agents in humans. Am J Obstet Gynecol 1994; 171: 653-60.
6. Langer O, et al. A comparison of glyburide and insulin in women with gestational diabetes mellitus. N Engl J Med 2000; 343: 1134- 8.
7. Garcia-Bournissen F, Feig DS, Koren G. Maternal-Fetal transport of hypoglycemic drugs. Clin Pharmacokinet 2003; 42: 303- 13.