POISON DETECTION AND DIAGNOSIS IN AYURVEDA: A HISTORICAL AND SCIENTIFIC PERSPECTIVE
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Keywords
Agadatantra, Visha, Forensic Toxicology, Visha Vega, Chaturvimshati Upakrama, Dushi Visha, Molecular Biomarkers.
Abstract
Agadatantra, the specialized branch of Ashtanga Ayurveda dedicated to toxicology, offers a profound historical framework for the detection and management of poisons (Visha). This paper provides a scientific redrafting of Ayurvedic toxicological principles, evaluating them through the lens of modern forensic science and molecular biology. The study analyzes the classification of toxins into Sthavara (inanimate), Jangama (animate), and Krutrima (artificial) categories, alongside the unique latent toxicity concept of Dushi Visha. We detail diagnostic methodologies such as Agni Pariksha (fire testing) and biological indicators, comparing them with contemporary Gas Chromatography-Mass Spectrometry (GC-MS) and clinical toxidromes. The pathophysiology is examined via Visha Vega (toxic impulses) and its molecular correlation with enzymatic degradation and systemic inflammatory responses. Finally, we evaluate the Chaturvimshati Upakrama (24 therapeutic modalities) against modern Advanced Cardiac Life Support (ACLS) and gastric decontamination protocols. The findings suggest that integrating Ayurvedic observational clinical skills with modern analytical precision offers a holistic and sustainable model for contemporary toxicology and medical jurisprudence.[i]
References
Vagbhata. (2002). Ashtanga Hridaya (H. S. Paradkar, Ed.). Uttara Sthana, Visha Pratishedha: Chapter 35, Shloka 7, Page 778. Chaukhamba Orientalia. (Original work published c. 7th Century CE).
Aebi, B. (2002). Gas chromatography-mass spectrometry (GC-MS) in today's forensic laboratory. Chimia, 56(1-2), 48-50. DOI: 10.2533/000942902777674751.
Charaka. (2020). Charaka Samhita (G. Krishna, S. Bhatt, & S. Binorkar, Trans.; Vol. 3). Chikitsa Sthana, Visha Chikitsa Adhyaya: Chapter 23, Shloka 14, Page 814. Charak Samhita Research Centre. (Original work published c. 1000 BCE–200 CE).
Sharangadhara. (2003). Sharangadhara Samhita (K. R. Murthy, Trans.). Prathama Khanda: Chapter 4, Shloka 22, Page 29. Chaukhamba Orientalia. (Original work published c. 14th Century CE).
Behera, N., et al. (2021). A critical interpretation on Gara Visha and Dushi Visha. International Journal of Emerging Technologies and Innovative Research, 10(3), g648-g654. DOI: 10.54060/ahr.2024.22.
Sushruta. (1911). Sushruta Samhita. Kalpa Sthana, Anna-pana-Raksha Adhyaya: Chapter 1, Shloka 29, Page 6.
Charaka. (2020). Charaka Samhita. Chikitsa Sthana, Visha Chikitsa Adhyaya: Chapter 23, Shloka 18-20, Page 815.
Vagbhata. (2006). Ashtanga Samgraha (S. Sharma, Ed.). Uttara Tantra, Visha Bheda Adhyaya: Chapter 40, Shloka 15, Page 914. Chaukhamba Sanskrit Series Office. (Original work published c. 6th Century CE).
Sanoop, S., et al. (2023). Conceptual study on action of Visha Gunas with snake venom compounds: A comparison. International Journal of Ayurveda and Pharma Research, 11(3), 95-101. DOI: 10.47060/ijapr.v11i3.2751.
Madhava. (2005). Madhava Nidana (S. Bhishagacharya, Ed.). Visha Nidana: Chapter 69, Shloka 1-5, Page 350. Chaukhamba Sanskrit Sansthan. (Original work published c. 7th Century CE).
Pathania, P. (2024). A classical and modern view on Visha Pareeksha: Review article. World Journal of Pharmaceutical Research, 13(23), 617-625. DOI: 10.20959/wjpr202423-32451.
Charaka. (2020). Charaka Samhita. Chikitsa Sthana, Visha Chikitsa Adhyaya: Chapter 23, Shloka 24-27, Page 816.
Sushruta. (1911). Sushruta Samhita. Kalpa Sthana, Sthavara-visha-vijnaniya Adhyaya: Chapter 2, Shloka 5, Page 15.
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Dr.Mohit Saini
PG Scholar, PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Dr. Ramkanwari Jakhar
PG Scholar, PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Prof. (Dr.) Ritu Kapoor
Professor and HoD PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Dr. Manoj Kumar Adlakha
Associate Professor PG Dept. Dravyaguna Vighyan, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
