EFFICACY OF COMBINED NIDIGDHIKA AVALEHA AND SHADBINDU TAILA NASYA IN THE MANAGEMENT OF VATAJA PRATISHYAYA (ALLERGIC RHINITIS): AN EXPLORATORY SINGLE-ARM CLINICAL STUDY
Main Article Content
Keywords
.................
Abstract
Vataja Pratishyaya is a complex, chronic, and recurrent inflammatory disorder characterized by cardinal symptoms such as sneezing, rhinorrhea, and nasal congestion, bearing a striking clinical resemblance to Allergic Rhinitis (AR). The etiology is intrinsically linked to Viruddha Ahara (incompatible diet) leading to Agnimandya (impaired digestion), resulting in the formation of Ama Visha (metabolic toxin). This Ama Visha exhibits the latent and hyper-reactive characteristics of Dushi Visha (latent poison), fueling chronic allergic sensitization.While conventional AR management offers symptomatic relief, it is often associated with recurrence and side effects.
Objective: To evaluate the clinical and objective efficacy of a combined therapy involving systemic Nidigdhika Avaleha and local Shadbindu Taila Nasya in the management of Vataja Pratishyaya (AR).
Methods: This was a single-arm, prospective interventional study involving 40 patients diagnosed with Vataja Pratishyaya (AR). Subjects received Nidigdhika Avaleha (6 g orally twice daily) and Shadbindu Taila Nasya (2 drops nasally twice daily) for a duration of 30 days. Efficacy was assessed using the Total Nasal Symptom Score (TNSS) for subjective parameters and objective laboratory markers: Absolute Eosinophil Count (AEC) and Erythrocyte Sedimentation Rate (ESR). Results: The combined therapy demonstrated highly significant clinical and objective efficacy (P < 0.0001$). The Total Nasal Symptom Score (TNSS) showed an overall improvement of 63.75%. Maximum symptomatic relief was observed for Nasal Itching (66.33%) and Rhinorrhea (65.45%). Objective markers of allergic inflammation confirmed systemic action, with a 50.94% reduction in the Absolute Eosinophil Count (AEC) and a 49.59% reduction in the Erythrocyte Sedimentation Rate (ESR).
Conclusion: The integrated administration of Nidigdhika Avaleha and Shadbindu Taila Nasya is significantly effective in managing Vataja Pratishyaya (Allergic Rhinitis), achieving substantial symptomatic relief and objective immunomodulation. Consequently, the null hypothesis, which states the therapy is ineffective, is rejected.
References
2. Ambikadatta Shastri K. (2019). Sushruta Saṃhita: Sutra sthan (Vol. 1). Reprint ed. Choukhambha Sanskrit Samsthan. (Chapter 46, verse 39). 1
3. Ambikadatta Shastri K. (2019). Sushruta Saṃhita: Uṭṭara Tantra (Vol. 2). Reprint ed. Choukhambha Sanskrit Samsthan. (Chapter 24, verses 1, 4, 5, 6, 16–17). 1
4. Bhavamishra. (2022). Bhavaprakasha, Nighantu, Indian Meteria Medica (Karpuradi Varga 66-67, Haritkyadi Varga 44-48). Commentary by K.C. Chunekar, edited by G.S. Pandey. Chaukhambha Sanskrit Sansthan. 1
5. Fischer D., Vander Leek T. K., Ellis A. K., Kim H. (2018). Anaphylaxis. Allergy Asthma Clin Immunol, 14(Suppl 2): 54. 1
6. Gupte V., Agrawal A., Shah A., Joshi K., Sood R., Mahesh P. A., et al. (2024). A perception-based survey on practice patterns pertaining to allergic rhinitis in India. Indian J Otolaryngol Head Neck Surg, 76(2), 145–153. 1
7. Kohli K. K. (2023, November 3). Allergic Rhinitis: Latest Practice Insights and Treatment Approach. Medical Dialogues. 1
8. Pereira C. D., Sharma A., Rajkumar S., Ghosh A., Kumar S., Singh R., et al. (2025). An Indian cross-sectional study to evaluate in-clinic allergic rhinitis prevalence in patients having nasal symptoms using the SFAR questionnaire. J Asthma Allergy, 18, 119-132. 1
9. Pt. Shastri H. Paradakar. (2012). Sarvanga Sundara of Arundatta & Ayurveda Rasayana of Hemadri, Ashtanga Hridaya. Chaukhamba Sanskrit Sansthana. (Sutrasthana 20/1-4, 20/34-36). 1
10. Scadding G. K. (1994). Allergic Rhinitis. In: Immunology of ENT Disorders (Vol. 23, pp. 93-116). Dordrecht: Springer. 1
11. Sastri K. (2018). Charakasaṃhita (Ca. Saṃh., ed. Kashinath Shastri) (Chikitsa Sthana 8:30, 8:49, 26:105). Reprint ed. Varanasi: Chaukhambha Sanskrit Samsthana. 1
12. Sharangdhara. (2010). Sharangadhara Samhita (Uttara Khanda 8/2, 8/6, 8/12, 8/16-17). Dipika Hindi Commentary by B. Tripathi. Chaukhamba Surabharati Prakashana. 1
13. Sastri R., Pandeya G. S. (2008). Vidhyotani Hindi Commentary. Chraka Samhita. (Vol. 1, Sutrasthana 5/46-47, 5/61-62). Choukhambha Bharati Academy. 1
14. Sastri R., Pandeya G. S. (2008). Vidhyotani Hindi Commentary. Chraka Samhita. (Vol. 2, Sidhisthana 9/88, 9/90, 9/107). Choukhambha Bharati Academy. 1
15. Vagbhata. (2016). Ashtanga Hridayam of Vagbhata (Uttara Sthana, Chapter 19, Shloka 3). Edited by A. D. Gupta. Chaukhamba Sanskrit Sansthanam. 1
16. Additional references for drug constituents and mechanisms are present in the source material and would be appended to the final publication's comprehensive bibliograp
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Anushka Chauhan
PG Scholar, PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Prof. (Dr.) Ritu Kapoor
Professor and HoD PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Prof. (Dr.) Devendra singh Chahar
Professor and HoD PG Dept. Of Maulik sidhanta evum samhita, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Dr. Manoj Kumar Adlakha
Associate Professor PG Dept. Dravyaguna Vighyan, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan
Dr.Praveen Kumar
Associate Professor PG Dept. Of Agadtantra evum vidhi vaidhyka, Post Graduate Institute of Ayurveda, DSRRAU Jodhpur Rajasthan