INCIDENCE OF COMORBIDITY OF VITAMIN D3 DEFICIENCY IN PATIENTS WITH DEPRESSIVE DISORDER AND CORRELATION OF THE DEFICIENCY WITH DEPRESSIVE SYMPTOMATOLOGY: A CROSS-SECTIONAL HOSPITAL-BASED STUDY
Main Article Content
Keywords
Depression; Vitamin D3 deficiency; Hamilton Depression Rating Scale; Comorbidity; Cross-sectional study
Abstract
Depressive disorder is a significant global public health issue with very high morbidity, mortality and socioeconomic cost. Recent studies anticipate the possibility of the relationship between the deficiency of Vitamin D3 and depressive disorders; nonetheless, the data on Indian clinical populations is insufficient.
Aim: To evaluate the comorbidity of Vitamin D3 deficiency in patients with depressive disorder and to assess the correlation between serum Vitamin D3 levels and severity of depressive symptomatology. Methods: This hospital-based cross-sectional study was conducted among 54 patients diagnosed with depressive disorder who attended the Psychiatry Outpatient Department of a tertiary care centre. The severity of depression was evaluated using the Hamilton Depression Rating Scale (HDRS), while serum Vitamin D3 levels were estimated and classified into appropriate categories. Descriptive statistical methods and correlation analysis were then used to explore the association between Vitamin D3 status and the severity of depressive symptoms.
Results: A high prevalence of suboptimal Vitamin D3 levels was observed, with Vitamin D insufficiency being the most common category. An inverse relationship was noted between serum Vitamin D3 levels and severity of depressive symptoms, with lower Vitamin D3 levels associated with greater depression severity.
Conclusion: Depression disorder is a disease with high levels of vitamin D3 deficiency and correlates with more severe depressive symptoms, which implies the possibility of using Vitamin D3 assessment in the clinical environment.
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Dr. Shubham Fojdar
Assistant Professor, Psychiatry, ESIC Medical College and Hospital, Address:ESIC Medical College and Hospital, Desula, MIA, Alwar, Rajasthan,
Dr Anu Meena
Assistant professor, OBGY, OBGY, ESIC Alwar, E-mail: [email protected]
Shubham Jhanwar
Assistant Professor, Psychiatry, ESIC Medical College and Hospital, ESIC Medical College and Hospital, Desula, MIA, Alwar, Rajasthan, E-mail: [email protected]
Alka Meena
Senior Resident, Psychiatry, ESIC Medical College and Hospital, ESIC Medical College and
Hospital, Desula, MIA, Alwar, Rajasthan, E-mail: [email protected]
