SEROPREVALENCE AND RISK FACTORS OF HUMAN PAPILLOMAVIRUS AMONG WOMEN ATTENDING A TERTIARY CARE CENTRE: A CROSS SECTIONAL STUDY
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Keywords
Human Papillomavirus, Prevalence, Molecular Analysis, Real-Time PCR, Socio-Demographic Factors
Abstract
Human papillomavirus (HPV) is recognized as the world’s most common sexually transmitted infection and a principal risk factor for cervical cancer. HPV infection rates continue to persist, especially in developing countries, where cervical cancer incidence and prevalence are still high. It is due to different reasons, which include low socioeconomic status, lack of population awareness, and inadequately implemented screening and vaccination programs. It is necessary to continue this discussion and to refocus the attention of specialists and the population worldwide on HPV infection and related diseases.
Aim and Objective:This study was conducted to determine the prevalence of HPV infection and firmly characterize the sociodemographic factors affecting its distribution among women.
Material and Methods: A cross-sectional cohort of 350 patients attending a tertiary care hospital’s gynecology outpatient department with collaboration with the department of Microbiology and Pathology with symptoms suggestive of genital infection was screened using Real-Time PCR for HPV genotyping. Sociodemographic, education, occupational, and economic variables were analyzed for correlation with infection rates.
Results: Among 350 women screened, 81 tested positive for HPV, giving a prevalence of 23.14%. Infection rates were highest among women aged 21-30 and those from rural backgrounds, with education and economic status significantly correlated to reduced prevalence.
Conclusion: The study confirms the substantial impact of sociodemographic determinants on HPV prevalence. Enhanced education and economic status were associated with lower infection rates, and public health initiatives should prioritize mass awareness and targeted screening.
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Dr. Jagjeewan Ram
Associate Professor1, Department of Pathology, Autonomous State Medical College, Kanpur Dehat, Uttar Pradesh, India.
Dr. Ashish Pal
Senior Resident2, Department of Microbiology, ESIC Medical College & Hospital, Pandeypur, Varanasi, Uttar Pradesh, India.
Dr. Amrita Shukla
Assistant Professor3, Department of Microbiology, Sri RawatpuraSarkar Institute of Medical Sciences and Research, Raipur, India.
Dr. Nashra Afaq
Assistant professor4, Department of Microbiology, Rama Medical College Hospital and Research Centre, Uttar Pradesh, India. ORCHID ID: 0000-0002-0069-6111
Dr. Roshni Agarwal
Associate Professor5, Department of Microbiology, Autonomous State Medical College, Kanpur Dehat,Uttar Pradesh, India.
Dr. Alok Kumar Arya
Associate Professor6, Department of Forensic Medicine and Toxicology, Rajarshi Dashrath Autonomous State Medical College, Ayodhya, India.
Dr. Atma Nand Yadav
Assistant professor7, Forensic medicine & toxicology, Era Medical College, Lucknow, Uttar Pradesh, India.
Dr. Manoj Kumar
Assistant Professor*, Department of Pathology, Autonomous State Medical College, Lakhimpur, Kheri, India.