ADULTS WITH DRY EYE DISEASE HAVE A HIGH RATE OF LATENT GRAM-NEGATIVE BACTERIA IN THEIR CONJUNCTIVA
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Keywords
Adults, Eye, Disease, Gram-Negative Bacteria
Abstract
In youthful adults with parched eye disease, the prevalence of conjunctival C.trachomatis (CT), M. hominis (MH), and U. urealyticum (UU) contamination is investigated since these contamination may possible state contribute to long term subclinical illness. There were 57 subjects with DED (n = 57) and 49 subjects with non-dry eye control (n = 49) in the study. Self-recorded problem, bio microscopy, Schirmer I test, and division were used to diagnose the condition. The conjunctivas of all patients were scraped and analyzed with undeviating fluorescent to make a specific immune response assay equipment for the detection of CT, MH, and UU. DED patients were more likely to have at least one of the three microorganisms than controls, with 87.7% having at least one of the three. DED patients who had CT, MH, or UU infections accounted for 63.2%, 50.8%, and 42.1% of all cases. Infectious DED patients were found to have multiple pathogens in 65% of cases. Controls had a CT infection rate of 6.1%. A tall wave passing of C.trachomatis, M.hominis, and U.urealyticum was found in the conjunctiva of youthful adults with DED, suggesting that these infections could be significant risk factors for DED.
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Dr. Pulgurthi Ramgopal
Associate Professor, Department Ophthalmology, Sri Lakshmi Narayana Institute of Medical Science, Pondicherry, India.
Dr.Shobana Ghanta
Assistant Professor, Department Ophthalmology, Sri Lakshmi Narayana Institute of Medical Science, Pondicherry, India.