SERUM ELECTROLYTES IN SUBCLINICAL HYPOTHYROIDISM

Abstract

Back ground: Thyroid hormones have various functions in the human body. They regulate body metabolism, hemodynamics, thermoregulation, and electrolyte balance. Hypothyroidism is accompanied by remarkable Changes in the metabolism of water and electrolytes. Hyponatremia is the commonest electrolyte imbalance in hypothyroid patients.

OBJECTIVE: The aim of our study is to find out electrolyte imbalance in subclinical hypothyroid patients.

MATERIAL And METHODS: This study was performed in 50 subclinical Thyroid Patients attending Endocrine OPD and 50 euthyroid Patients attending general OPD in Government Mohan kumaramangalam medical college and hospital and 5ml of venous blood sample will be collected and analysed TSH, FT4 in fully automated hormone analyser (Eclia) and serum sodium and potassium was analysed in medica electrolyte analyser The statistical analysis was performed using SPSS version 16.

Results: The distribution of Sodium values is not the same between normal and subclinical groups .90% of Subclinical cases has hyponatremia compared to 16% of normal cases. This strongly indicates that there is a statistically significant association between Thyroid status and Sodium levels. The distribution of Potassium values is not the same between normal and subclinical groups .80% of Subclinical cases has hypokalemia compared to 10% of normal cases. This strongly indicates that there is a statistically significant association between Thyroid status and potassium levels.

Conclusion: In our study we found there is a decrease in serum sodium and serum potassium levels in subclinical hypothyroid patients when compared to healthy controls. Routine Screening of subclinical hypothyroid patients will be more helpful during the management of thyroid patient’s prevention of further complications.