ANTIMICROBIAL ACTIVITY OF BLACK TEA WITH GINGER FORMULATIONS AND ITS CYTOTOXIC EFFECT—IN VITRO STUDY
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Keywords
Ginger, Black Tea, Antimicrobial, Cytotoxicity, Herbal Formulation, Brine Shrimp Assay
Abstract
Background: Black tea and ginger are well-known for their therapeutic and antimicrobial properties. This study aimed to evaluate the combined antimicrobial efficacy and cytotoxicity of black tea and ginger extract formulations in vitro..
Methods: Black tea-ginger extract combinations were prepared and tested for antimicrobial activity using agar well diffusion and cytotoxicity using brine shrimp lethality assay.
Results: The formulation exhibited dose-dependent antimicrobial activity against tested pathogens and showed minimal cytotoxicity at lower concentrations.
Conclusion: Black tea with ginger formulations demonstrated potential as a natural antimicrobial agent with acceptable cytotoxicity, encouraging further exploration in pharmaceutical and dental applications.
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M.Vignesh
Saveetha Dental college and Hospitals, Saveetha Institute of Medical and Technical sciences, Saveetha university, Chennai 77, Tamil Nadu,India.
S. Rajeshkumar
Associate Professor, Department of Pharmacology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai 77, Tamil Nadu, India.
Balaji Ganesh
Scientist, White lab - Materials Research Centre, Saveetha Dental College and Hospital, Saveetha Institute of Medical & Technical Sciences (SIMATS) Chennai-600077