HYPERCORTISOLISM AND ITS CORRELATION WITH DIFFERENT ASPECTS OF METABOLIC SYNDROME
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Keywords
Metabolic syndrome, Serum cortisol, Cushing’s syndrome, Obesity.
Abstract
Serum Cortisol is a stress hormone released in acute and chronic stressful conditions. Association with non-infective and lifestyle diseases is an area of ongoing research. Metabolic syndrome (MetS) is expected to be low grade indolent chronic inflammatory state. To investigate the same, we designed a cross-sectional study of 100 subjects including 50 diagnosed cases of metabolic syndrome and 50 healthy controls in whom fasting serum cortisol values were measured and compared with different parameters of MetS. Raised serum cortisol levels were seen in 62%(n=31) cases with a mean value of 26.11 ± 11.63 mcg/dL as compared to controls with no sex predilection. Significant association of high cortisol levels were seen with raised fasting glucose and low serum HDL levels.
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Saurabh Gupta
Assistant Professor, Department of Medicine, Pacific Medical College and Hospital, Udaipur, Rajasthan
Korat Akash Hasmukh bhai
Junior Resident, Department of Medicine, Pacific Medical College and Hospital, Udaipur, Rajasthan
Poonam Gupta
Specialist Ophthalmologist, ESIC Hospital, Udaipur, Rajasthan
Mukul Sharma
Assistant Professor, Department of Biochemistry, Pacific Medical College and Hospital, Udaipur, Rajasthan