COMPARISON BETWEEN TREATMENT OF ORAL SUBMUCOUS FIBROSIS WITH INTRALESIONAL TRIAMCINOLONE INJECTION VERSUS PLATELET RICH PLASMA
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Keywords
Oral Submucous Fibrosis, Platelet-Rich Plasma, Triamcinolone, Intralesional Injection, Mouth Opening, Burning Sensation
Abstract
Introduction: Oral Submucous Fibrosis (OSMF) is a chronic and advancing oral condition that develops after consumption of areca nut, resulting in diminished mouth functionality and burning mouth symptoms.
Objective: Whether intralesional triamcinolone injections produce comparable clinical effects to platelet-rich plasma (PRP) therapy when treating OSMF.
Materials and Method: The study was done on patients who received an OSMF diagnosis. The study divided patients between two therapeutic options: intralesional triamcinolone or PRP treatment. The study delivered both therapeutic solutions once weekly for eight weeks. The study evaluated treatment results based on the patients' improvement of mouth movement alongside the decrease in the severity of their burning sensation.
Results: A clinical evolution was detected in all patients. Attempts to enhance mouth opening combined with symptom relief using PRP yielded better long-term results compared to triamcinolone, where adverse effects remained lower for PRP patients.
Conclusion: Long-term research on PRP indicates its functions better than corticosteroid therapy for treating OSMF while maintaining excellent compatibility with the body tissue.
References
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Dr. Madiha Khan
BDS, MS Scholar- PG Trainee, Karachi Metropolitan University/ Abbasi Shaheed Hospital, Pakistan
Dr. Sufyan Ahmed
BDS, FCPS (OMFS), HOD oral and Maxillofacial Surgery Department KMDC/KMU and ASH, Karachi Metropolitan University/ Abbasi Shaheed Hospital, Pakistan
Dr. Aisha Faraz
BDS, MS Scholar- PG Trainee, Karachi Metropolitan University/ Abbasi Shaheed Hospital, Pakistan
Dr. Zahid Ali
BDS, FCPS (OMFS), PHD Scholar, Professor Oral and Maxillofacial Surgery, Karachi Metropolitan University/ Abbasi Shaheed Hospital, Pakistan
Dr. Sobia Khan
BDS, CHPE, MS- OMFS (Scholar), PG Trainee, Abassi Shaheed Hospital, Pakistan
Dr Mahrukh Iqbal
BDS, CHPE, MS-OMFS (SCHOLA.R) PG-R, Abbassi Shaheed Hospital/KMDC, Pakistan