PREVALENCE OF ACUTE KIDNEY INJURY AMONG PEDIATRIC PATIENTS HOSPITALIZED WITH ACUTE GASTROENTERITIS
Main Article Content
Keywords
Acute gastroenteritis, acute kidney injury, pediatrics, dehydration, KDIGO, Pakistan
Abstract
Introduction: Acute gastroenteritis (AGE) is a leading cause of pediatric hospitalization, and it is found that acute kidney injury (AKI) related to AGE is more common in resource-constrained environments. It is about the timely diagnosis and management of AKI in any such cases, which is still a clinical concern.
Objective: To determine the prevalence of acute kidney injury among pediatric patients hospitalized with acute gastroenteritis at a tertiary care center and identify associated risk factors.
Materials and Method: A cross-sectional descriptive study was carried out at the Department of Pediatrics, Services Hospital Lahore, from January to June 2024. Thus, the data of 200 children aged 1 month to 14 years, admitted with AGE, were enrolled in the study. The diagnosis of AKI was established based on KDIGO criteria, and the patient’s clinical and laboratory features were compared. Statistics were performed using SPSS software version 26.
Results: Overall, 29% of patients developed AKI, most of them being males and children in the age group 1-5 years. One of the significant causes attributable to this is severe dehydration. Most of the cases can be managed conservatively.
References
2. Marzuillo, P., Baldascino, M., Guarino, S., Perrotta, S., Miraglia del Giudice, E. and Nunziata, F., 2021. Acute kidney injury in children hospitalized for acute gastroenteritis: prevalence and risk factors. Pediatric Nephrology, 36, pp.1627-1635.
3. Jamal, N., Banaras, F., Ashfaq, M., Tahir, T., Jadoon, I. and Raza, A., 2022. Incidence of Acute Kidney Injury (AKI) Secondary to Acute Gastroenteritis in Patients Presenting to Ayub Teaching Hospital, Abbottabad. Pakistan Journal of Medical & Health Sciences, 16(12), pp.537-537.
4. Poddar, C., Behera, J.R., Barik, R.R. and Meher, A.K., 2023. A Tertiary Care Experience is provided for Acute Kidney Injuries under 14 Years of Age. Journal of Cardiovascular Disease Research, 14(12), pp.21-28.
5. Parikh, A.C. and Tullu, M.S., 2021. A study of acute kidney injury in a tertiary care pediatric intensive care unit. Journal of Pediatric Intensive Care, 10(04), pp.264-270.
6. Ezeonwu, B.U., Abonyi, L.E., Odetunde, O.I., Nnodim, I.J., Nwafor, I.O., Ajaegbu, O.C., Emeagui, O.D., Okoli, N.E. and Okolo, A.A., 2021. Epidemiology of community-acquired acute kidney injury in children as seen in an emergency room of Tertiary Hospital in South-South Nigeria. Saudi Journal of Kidney Diseases and Transplantation, 32(2), pp.428-436.
7. Haridas, N., Thirumavalavan, S., Fernando, M.E., Vellaisamy, M., Annadurai, P., Srinivasaprasad, N.D., Surendran, S., Valavan, K.T., Joseph, J. and Gayathri, M.S., 2024. Post-diarrheal acute kidney injury during an epidemic in monsoon–a retrospective study from a tertiary care hospital. Indian Journal of Nephrology, 34(4), p.338.
8. Elbeunishi, A., Algadban, F. and Al Alajilani, W., 2024. Acute Kidney Injury in Pediatric Intensive Care Unit: Incidence, Risk Factors, and Outcome. Libyan Medical Journal, pp.246-254.
9. Paudel, R., Shah, G.S., Chaudhary, S., Dharel, D. and Timilsina, A., 2021. Incidence and outcome of acute kidney injury in hospitalised children. Journal of Nepal Paediatric Society, 41(1), pp.80-86.
10. Javaid, M.S., Basheer, F. and Ateeq, S., 2022. Clinical Profile and Outcome of Renal Replacement Therapy in a Pediatric Intensive Care Unit of a Tertiary Care Hospital. Pakistan Armed Forces Medical Journal, 72, p.S200.
11. Das, P.C., Kulhar, A., Thomas, M.S., Patel, S.B. and Mittal, P., 2021. Incidence and risk factor profile of adult patients with acute kidney injury admitted to a tertiary care centre of North India. Int J Med Sci Clin Res, 3(1), pp.25-31.
12. Rivetti, G. and Marzuillo, P., 2023. Community-Acquired Acute Kidney Injury in Hospitalized Children: Do Not Miss the Diagnosis. Indian. Paediatr, 60, pp.433-434.
13. Sharma, R., 2021. Clinical Profile and Epidemiology of Neonates Presenting with Acute Gastroenteritis with Special Emphasis on Acute Kidney Injuryby Raman Sharma, Vipul Taneja, Kajal Khajuria, Rasmeen Kaur, AK Bhardwaj.
14. Kazi, S., Majumdar, R. and Mahajan, D., 2025. Assessment of electrolyte imbalance and its predictors in children admitted with Acute Gastroenteritis-Cross Sectional study. Indian Journal of Child Health, 12(2).
15. Lone, Y., Chaudhry, A.R. and Ayub, R., 2024. Frequency and outcomes of acute kidney injury in pediatric intensive care unit. The Professional Medical Journal, 31(12), pp.1638-1643.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Zainab Abbas
Medical Officer, Tahir Medical Clinic, Pakistan
Syeda Batool Kazmi
MBBS, MRCP CH, Senior Medical Officer, Khoula Hospital Muscat, Oman
Ayesha Abbas
Medical Officer, Tahir Medical Clinic, Pakistan
Tufail Ahmed Soomro
Assistant Professor, GMMMC Hospital Sukkur, Pakistan
Fareeha Abbas
Senior Registrar, Azra Naheed Medical College, Pakistan
Saima Ghafoor
Senior Registrar, Paediatrics Shalamar Medical and Dental College, Pakistan