HISTOPATHOLOGICAL SPECTRUM OF NASAL POLYPS: A RETROSPECTIVE ANALYSIS OF 200 CASES
Main Article Content
Keywords
Nasal polyps, histopathology, inflammatory polyps, allergic polyps, fungal sinusitis, retrospective study
Abstract
Introduction: Nasal polyps are derived from the mucosal lining of the nasal cavity or paranasal sinuses and are benign outgrowths. They are often seen with symptoms of nasal obstruction, rhinorrhea, and decreased sense of smell. However, it is important to note that accurate diagnosis and subclassification depend on histopathological evaluation.
Objective: In a retrospective cohort of 200 nasal polyp cases, the histopathological spectrum was to be analyzed to obtain the predominant types, associated features, and clinical significance.
Materials and Method: The study is done in the Department of Pathology, Niazi Medical College Sargodha, Pakistan, from December, 2024 to March, 2025. Biopsy specimens from 200 specimens were processed, stained with H&E, and evaluated microscopically. Morphological features of polyps were used to classify them.
Results: The most common type of polyp was inflammatory (48.5%), followed by allergic (34%) and fungus (10.5%). Geographically, male predominance and peak incidence were observed in the 31–50-year-old age group.
References
2. Abdulla, M.S., Janardhan, K., Lakshmi, V.P. and John, R., 2024. A Retrospective Study on Histomorphological Analysis of Sinonasal Polyps at A Tertiary Care Centre in A Rural Area of South India. Int. J. Trop. Med, 18, pp.83-89.
3. Fiorentino, V., Martini, M., Galletti, C., Pizzimenti, C., Franchina, M., Ieni, A., Fadda, G., Galletti, B. and Tuccari, G., 2024. The morphology of nasal polyps in different age groups: histopathological features. Journal of Personalized Medicine, 14(4), p.414.
4. Rajitha, J. and Srikanth, S., 2021. Spectrum of Histopathological Study of Lesions of Nasal cavity and Paranasal Sinuses–A two years study. Sch J App Med Sci, 3, pp.378-380.
5. Prasad, K.C., Varsha, G.I., Mohammadi, K., Gupta, A. and Jose, D.A., 2024. A Clinicopathological Study of Aural Polyps: A Retrospective Analysis in a Tertiary Care Hospital. International Archives of Otorhinolaryngology, 28(03), pp.e368-e373.
6. Singh, A., Singh, S., Dhillon, V., Parihar, L.S., Yadav, K. and Kamra, H., 2024. SPECTRUM OF HISTOPATHOLOGICAL LESIONS OF NASAL CAVITY, NASOPHARYNX AND PARANASAL SINUSES. Int J Acad Med Pharm, 6(3), pp.362-365.
7. Kandasamy, S., Chandrasekar, M. and Ramachadran, T., 2021. Histopathological Examination in the Categorization of Fungal Rhinosinusitis-a Retrospective Study. Nepalese Medical Journal, 4(2), pp.478-481.
8. Iordache, A., Balica, N.C., Horhat, I.D., Morar, R., Tischer, A.A., Milcu, A.I., Salavat, M.C., Borugă, V.M., Niculescu, B., Iovănescu, G. and Popa, Z.L., 2022. Allergic rhinitis associated with nasal polyps and rhinosinusitis–histopathological and immunohistochemical study. Romanian Journal of Morphology and Embryology, 63(2), p.413.
9. Hossain, T. and Hanif, M.A., 2023. Histopathological Spectrum of Sinonasal Masses in Patients Coming To a Tertiary Care Hospital: A Study of 150 Cases. Saudi J Med Pharm Sci, 9(2), pp.56-60.
10. Bhagat, R., 2024. Role of histopathological and microbiological investigations for a definitive diagnosis of benign sinonasal masses: a tertiary care institute study. International Journal of Research in Medical Sciences, 12(3), p.764.
11. Lambor, S., Varughese, K.M., Naik, A., Lambor, D.V., Tiwari, M. and De Sa, C.J., 2024. A Retrospective Analysis of Clinicopathological Features in 117 Isolated Maxillary Sinus Pathologies in a Tertiary Care Hospital. Indian Journal of Otolaryngology and Head & Neck Surgery, 76(2), pp.1931-1940.
12. Prajapati, J.A., Patel, K.J., Dangi, J.M. and Vaghela, K., 2024. A RETROSPECTIVE HISTOPATHOLOGICAL ANALYSIS OF NASOPHARYNGEAL LESIONS AT A TERTIARY LEVEL INDIAN HOSPITAL. Journal of Cardiovascular Disease Research, 15(3), pp.121-126.
13. Birare, S.D. and Chaudhari, A.S., 2021. Clinicopathological study of lesions of nasal cavity and paranasal sinuses-A two year study. IP J Diagn Pathol Oncol, 6, pp.259-66.
14. Dongapure, S., Shankar, A.A. and Parthibhan, R., 2023. A clinicopathological study of sinonasal lesions-5 years study in a rural hospital setup. Journal of Pathology of Nepal, 13(1), pp.1987-1992.
15. Dewi, Y. and Sugiharto, S., 2024. Histopathological Study of Sinonasal and Nasopharyngeal Lesions in Sumber Waras Hospital Jakarta from 2017-2023. Jurnal Kedokteran Diponegoro (Diponegoro Medical Journal), 13(4).
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Sabah Kaleem Baloch
Associate Professor, Department of of Pathology, Niazi Medical College Sargodha, Pakistan
Maqbool ahmed Baloch
Associate Professor, Department of ENT, Niazi Medical College Sargodha, Pakistan