COMPARATIVE OUTCOMES OF HEMODIALYSIS VS PERITONEAL DIALYSIS IN END-STAGE RENAL DISEASE PATIENTS: A SYSTEMATIC REVIEW AND META-ANALYSIS
Main Article Content
Keywords
End-stage renal disease, hemodialysis, peritoneal dialysis, dialysis outcomes, mortality, quality of life, renal replacement therapy, comparative analysis
Abstract
Background
End-stage renal disease (ESRD) necessitates renal replacement therapy, primarily through hemodialysis (HD) or peritoneal dialysis (PD). The results from implementing these treatment methods create ongoing disputes because they alter depending on patient characteristics and healthcare organizations.
Objectives
The research examines how dialysis through hemodialysis (HD) or peritoneal dialysis (PD) influences survival rates and quality of life and cardiovascular complications and cost-effectiveness in ESRD patients.
Methodology
An extensive review of peer-reviewed articles which covered the time period from 1999 to 2024 has been performed systematically. The research selection process relied on specific criteria that prioritized outcome data comparisons. The assessment included the analysis of pooled hazard ratios for determining mortality and hospitalization risk and patient-reported outcome results.
Results
Current evidence shows no consistent survival advantage of either modality in the general ESRD population. PD maintains the original kidney function better while providing superior value for money and better early outcomes according to patient reports of their quality of life. The choice of hemodialysis is appropriate for heart unstable patients and those in advanced age categories. Effectiveness of modality treatments in ESRD patients depended on geographic factors along with infrastructure conditions.
Conclusion
ESRD treatment stays viable through HD and PD yet the selection of patients and local healthcare environments determine patient outcomes. Patient-specific care plans require inputs from clinical profiles and patient preferences for the selection of optimal therapy options.
References
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Farha Jabeen
Rehman Hospital, Faisalabad, Pakistan
Mumin Idris
Gulf Medical University, Ajman, UAE
Marium Nadeem Khan
Shifa College of Medicine, Islamabad, Pakistan
Ali Sanan Ahmed
Third Year MBBS, Shifa College of Medicine, Islamabad, Pakistan
Mahnoor Zafar
Rawalpindi Medical University, Rawalpindi, Pakistan
Muhammad Shahreyar
Third Year MBBS, Shifa College of Medicine, Islamabad, Pakistan
Abeeha Mahmood
Third Year MBBS, CMH Lahore Medical College, Lahore, Pakistan
Maha Masood
CMH Lahore Medical College, Lahore, Pakistan
Rida Ahmed
RAK Medical & Health Sciences University, Ras AL-Khaimah, UAE
Gousiya Fathima
RAK Medical & Health Sciences University, Ras AL-Khaimah, UAE
Nadya Hasan Rahman
RAK Medical & Health Sciences University, Ras AL-Khaimah, UAE
Fathima Suha Mohamed Rafeeq
RAK Medical & Health Sciences University, Ras AL-Khaimah, UAE