BACTERIOLOGICAL PROFILE OF SURGICAL SITE INFECTIONS ALONG WITH THEIR ANTIBIOGRAM AT A TERTIARY CARE HOSPITAL IN A RURAL AREA OF JHARKHAND.
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Keywords
Antibiotic, surgical site infection, SSI, bacteria, infection
Abstract
Introduction- Surgical site infection (SSI) is one of the significant post-operative complications. SSIs can be prevented by determining the factors causing post-operative infection, which then helps in proper antibiotic medication and improving infection control methods. However reducing post-operative infection has grown more difficult due to the increased bacterial resistance to antibiotics. Only few data is available regarding SSI and their antibiogram from countries like India, where healthcare system is not much developed. So this study was conducted to determine the bacteriological profile of surgical site infections as well as their antibiogram at a tertiary care hospital.
Material and method- The present study was a descriptive cross-sectional study carried out on 82 clinically suspected SSI patients. Swabs from surgical site were collected aseptically and then processed within 30 minutes. The laboratory samples were prepared for aerobic culture, direct microscopy, and sensitivity in compliance with standard methods. The data were analyzed using SPSS version 20 and p-value less than 0.05 was considered statistically significant.
Result- In present study laboratory findings revealed 68.29% of the samples to be positive for bacterial infection A statistically significant association of bacterial positivity with age, surgical duration and cardiac disease was observed. Our study showed predominance of Gram-negative bacteria over gram-positive bacteria. Among the gram-positive bacteria, Staphylococcus spp. and among the Gram-negative bacteria, Escherichia coli (E. coli) were the most common. The most effective antibiotics against gram-positive bacteria were Ofloxacin, Ampicillin, and Clindamycin. Highly effective antibiotics against gram negative bacteria included Aztreonam, Meropenem, Imipenem, Cefepime, and Amoxicillin-Clavulanate.
Conclusion- The observed antimicrobial resistance trends emphasize the need for continuous surveillance and rational antibiotic use. Focus should be on preventive measures, including optimizing surgical practices and improving antimicrobial stewardship, to reduce the incidence of SSIs and improve patient outcomes.
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Dr Om Prakash Bharati
Assistant Professor, Department of Microbiology, Laxmi Chandravansi Medical College and Hospital, Palamu, India
Dr Kasturi
Assistant Professor, Department of Microbiology, Laxmi Chandravansi Medical College and Hospital, Palamu, India
Dr Srishti Gunjan
Assistant Professor, Department of Microbiology, Laxmi Chandravansi Medical College and Hospital, Palamu, India