PREVALENCE OF THYROID DYSFUNCTION IN NAMAKKAL DISTRICT -A HOSPITAL-BASED STUDY.
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Keywords
Prevalence, thyroid dysfunction,Hypothyroidism, Hyperthyroidism, Subclinical Hypothyroidism, Subclinical Hyperthyroidism, secondary hypothyroidism
Abstract
Introduction: Thyroid disorders are most common endocrine disorder in India but the prevalence studies on these dysfunction is limited.
Materials and method: All subjects who visited the hospital for a period of four months to have thyroid function tests (TFTs) on their first outpatient visit were included in the study.
Results: Thyroid disordrs were present in 22.11 % of the total 2510 subjects . The prevalence rate was higher in females (64.8%) than males (35.2%) with (p=0.0003).
The prevalence of hypothyroidism in the study population was 64.32 % (n = 357). In our study those with primary hypothyroidism were predominant (55.18 %, 197 out of 357) and 43.1 % (154 out of 357) were having sub clinical hypothyroidism and 6 of 357 were having secondary hypothyroidism.The prevalence rate of hyperthyroidism was 52.6 % (n-188) . The majority were subclinical hyperthyroidism (65.90 % , 124 out of 188) ,30.8 % (58 out of 188) had primary hyperthyroidism and3% ( 6 out of 188) had secondary hyperthyroidism
Conclusion: In our study thyroid function abnormalities were noted in 15.73 % of all subjects. Thyroid disorders were common in age of >20 years than 20-40 ,40-60 and and >60 year categories. The prevalence of primary hypothyroidism was found to be higher than subclinical hypothyroidism,while in hyperthyroidism subclinical condition was predominant compared to primary hyperthyroidism.
References
2. 2.Yadav NK, Thanpari C, Shrewastwa MK, Sathian B, Mittal RK. Socio demographic wise risk assessment of thyroid function abnormalities in far western region of Nepal: A hospital based descriptive study. Asian Pac J Trop Dis. 2013 ;3(2):150–4.
3. Unnikrishnan AG, Menon UV. Thyroid disorders in India: An epidemiological perspective. Indian J Endocrinol Metab. 2011 ;15(Suppl 2):S78-81.
4. 4.Devaraj, T. V, Salina, S.1. Prevalence of hypothyroidism in Kannur; a coastal district in Kerala. Thyroid Research and Practice, 2021; 18(2):p 55-60.
5. Fabrizio Monaco, Classification of Thyroid Diseases: Suggestions for a Revision. The Journal of Clinical Endocrinology & Metabolism. 2003 ; 88( 4) 1, 1428–1432.
6. Mulder JE. Thyroid disease in women. Medical Clinics of North America. 1998 ; 1;82(1):103-25.
7. Gietka-Czernel M. The thyroid gland in postmenopausal women: physiology and diseases. Prz Menopauzalny. 2017 ;16(2):33-37.
8. Mahanta, Anindita; Choudhury, Sushmita, Choudhury, Sarojini Dutta . Prevalence of hypothyroidism in Assam: A clinic-based observational study. Thyroid Research and Practice.2017; 14(2): 63-70.
9. Xie Y, Wang Z, Chen Z. Analysis of Subclinical Thyroid Dysfunction and Metabolic Abnormality in 28568 Healthy People. International Journal of Endocrinology. 2023 ; 2024, 8414689.
10. 10.Velayutham K, Selvan SS, Unnikrishnan AG. Prevalence of thyroid dysfunction among young females in a South Indian population. Indian J Endocrinol Metab. 2015 ;19(6):781-4.
11. Usha Menon V, Sundaram KR, Unnikrishnan AG, Jayakumar RV, Nair V, Kumar H. High prevalence of undetected thyroid disorders in an iodine sufficient adult south Indian population. J Indian Med Assoc. 2009;107:72–7.
12. Abraham R, Srinivasa Murugan V, Pukazhvanthen P, Sen SK. Thyroid disorders in women of Puducherry. Indian J Clin Biochem. 2009;24:52–9. 10.1007/s12291-009-0009-y
13. Delitala AP, Scuteri A, Doria C. Thyroid Hormone Diseases and Osteoporosis. J Clin Med. 2020 r 6;9(4):1034.
14. Alqahtani SAM. Prevalence and Characteristics of Thyroid Abnormalities and Its Association with Anemia in ASIR Region of Saudi Arabia: A Cross-Sectional Study. Clin Pract. 2021 6;11(3):494-504.
15. The consortium on thyroid and pregnancy—study group on preterm birth. Association of thyroid function test abnormalities and thyroid autoimmunity with preterm birth: A systematic review and meta-analysis. JAMA. 2019;322(7):632–41.
16. Mulder JE. Thyroid disease in women. Med Clin North Am. 1998 ;82(1):103-25.
17. Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 2004;291:228–38
18. Nair A, Jayakumari C, Jabbar PK, Jayakumar RV, Raizada N, Gopi A, et al. Prevalence and associations of hypothyroidism in Indian patients with type 2 diabetes mellitus. J Thyroid Res. 2018;5386129.19.
19. Kalra S, Aggarwal S, Khandelwal D. Thyroid Dysfunction and Type 2 Diabetes Mellitus: Screening Strategies and Implications for Management. Diabetes Ther. 2019 ;10(6):2035-2044.
20. Kalra S, Aggarwal S, Khandelwal D. Thyroid Dysfunction and Type 2 Diabetes Mellitus: Screening Strategies and Implications for Management. Diabetes Ther. 2019 Dec;10(6):2035-2044.
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Sachu Philip
PhD, Associate Professor, Department of Biochemistry, Swamy Vivekanandha Medical College Hospitals And RI, Elayampalayam, Tiruchengode, Namakkal, Tamil Nadu, India
Philips Abraham
PhD, Professor, Department of Biochemistry, AL AZHAR Medical College & Hospitals, Thodupuzha, Kerala