DIAGNOSTIC EVALUATION OF BISAP SCORING SYSTEM ON PREDICTING SEVERITY OF ACUTE PANCREATITIS
Main Article Content
Keywords
Acute Pancreatitis; BISAP; Severity Prediction.
Abstract
Background
Acute pancreatitis is a significant health concern requiring timely evaluation and management. It can lead to multi-organ dysfunction and increased mortality. The BISAP (Bedside Index of Severity in Acute Pancreatitis) is a simple scoring system that assesses severity at admission using routine clinical and laboratory parameters. This study evaluates the effectiveness of BISAP in predicting acute pancreatitis severity.
Methods
A cross-sectional study was conducted on acute pancreatitis cases admitted to the Department of General Surgery, Government Medical College, Thiruvananthapuram, over one year. Patients were assessed using the BISAP score at admission and followed up at seven days and six weeks. The BISAP score was compared with the Revised Atlanta Classification 2012 for severity grading. Statistical analysis was performed using appropriate software.
Results
Among 60 patients (49 males, 11 females; mean age 40.2±15.8 years), 47 had mild, 4 had moderately severe, and 9 had severe acute pancreatitis based on the Revised Atlanta Classification. Thirteen patients had a BISAP score indicative of severe pancreatitis. The BISAP score showed 100% sensitivity, 92.2% specificity, and 93.3% overall accuracy in predicting severity. The positive predictive value was 69.2%, and the negative predictive value was 100%. Six early deaths occurred, all classified as severe by BISAP. The BISAP score also had 100% sensitivity and NPV in predicting mortality (p < 0.01).
Conclusion
The BISAP score is a reliable predictor of severity and mortality in acute pancreatitis. It enables early
References
[2] Appelros S, Borgström A. Incidence, aetiology and mortality rate of acute pancreatitis over 10 years in a defined urban population in Sweden. Br J Surg 1999;86(4):465-70.
[3] Lowenfels AB, Maisonneuve P, Sullivan T. The changing character of acute pancreatitis: Epidemiology, etiology, and prognosis. Curr Gastroenterol Re. 2009;11(2):97–103.
[4] Enite AM, El Badawy HA. Role of multidetector CT in diagnosis and classification of acute pancreatitis. Al-Azhar Med J 2015;43(1):179–89.
[5] Sarr MG, Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, et al. The New Revised Classification of Acute Pancreatitis 2012. Surg Clin North Am 2013;93(3):549–62.
[6] Fu CY, Yeh CN, Hsu JT, Jan YY, Hwang TL. Timing of mortality in severe acute pancreatitis: Experience from 643 patients. World J Gastroenterol 2007;13(13):1966-9.
[7] Khanna AK, Meher S, Prakash S, Tiwary SK, Singh U, Srivastava A, et al. Comparison of Ranson, Glasgow, MOSS, SIRS, BISAP, APACHE-II, CTSI scores, IL-6, CRP, and procalcitonin in predicting severity, organ failure, pancreatic necrosis, and mortality in acute pancreatitis. Hpb Surg 2013;2013.
[8] Kumaravel A, Jayaraman R, Kandasamy S, Periyasamy S. Prognostic value of BISAP score in acute pancreatitis: a prospective study. Int Surg J 2018;5(2):354-9.
[9] Singh VK, Wu BU, Bollen TL, Repas K, Maurer R, Johannes RS, et al. A prospective evaluation of the bedside index for severity in acute pancreatitis score in assessing mortality and intermediate markers of severity in acute pancreatitis. Am J Gastroenterol 2009;104(4):966.
[10] Mounzer R, Langmead CJ, Wu BU, Evans AC, Bishehsari F, Muddana V, et al. Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis. Gastroenterology 2012;142(7):1476-82.
[11] Singh VK, Wu BU, Bollen TL, Repas K, Maurer R, Johannes RS, et al. Early systemic inflammatory response syndrome is associated with severe acute pancreatitis. Clin Gastroenterol Hepatol 2009;7(11):1247-51.
[12] Mutinga M, Rosenbluth A, Tenner S, Whitcomb DC, Banks PA. Multiple organ failure, rather than pancreatic necrosis, predicts fatal outcome in severe acute pancreatitis. Gastroenterology 2000;119(3):899-906.
[13] Papachristou GI, Whitcomb DC. Predicting severe acute pancreatitis: current knowledge and novel insights. World J Gastroenterol 2007;13(44):6442-50.