A CROSS-SECTIONAL STUDY ON ASSESSMENT OF CT PERFUSION IMAGING IN ACUTE ISCHEMIC STROKE: CLINICAL BENEFITS AND LIMITATIONS
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Keywords
CT perfusion, acute ischemic stroke, imaging, clinical benefits,, limitations
Abstract
Background: Acute ischemic stroke (AIS) is a leading cause of morbidity and mortality worldwide, necessitating rapid and accurate diagnosis for timely intervention [1]. CT perfusion (CTP) imaging is increasingly utilized to assess cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT), aiding in differentiation between salvageable tissue and irreversibly damaged infarct core CT perfusion (CTP) imaging has emerged as a crucial tool in the evaluation of acute ischemic stroke (AIS). This cross-sectional study assesses the clinical benefits and limitations of CTP in the diagnosis and management of AIS. Materials and methods: This cross-sectional study was conducted on 150 patients who presented with suspected AIS within 24 hours of symptom onset. Inclusion criteria comprised adult patients (≥18 years) with neurologic deficits consistent with stroke. Exclusion criteria included contraindications to contrast media or prior intracranial hemorrhage Data from 150 patients presenting with suspected AIS were analyzed for imaging accuracy, treatment decision impact, and functional outcomes. Results and conclusion: CTP effectively identified ischemic penumbra and core infarct in 87% of cases, improving thrombolysis decisions. However, limitations included radiation exposure, variability in perfusion thresholds, and technical artifacts. Overall, CTP enhances stroke triage and treatment but requires careful interpretation to minimize false positives and negatives.
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Dr. Rahul Bhagwat Mane
Assistant Professor, Dept. of Radiodiagnosis, RKDF Medical College Hospital and Research Centre, Bhopal, Madhya Pradesh.