EFFICACY OF SURFACTANT ADMINISTRATION VIA MIST TECHNIQUE VERSUS INSURE TECHNIQUE IN PRETERMS
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Abstract
Introduction: Neonatal respiratory distress syndrome (RDS) refers to the insufficiency of the lungs. INSURE approach, named after the key three stages in the procedure: INtubation, SURfactant administration and then Extubation as quickly as possible after administration. Minimally invasive surfactant therapy (MIST) administers surfactant into the trachea by direct laryngoscopy.
Aim: To measure the outcome of preterm infants (24-36wks) born with RDS who receives surfactant therapy via MIST technique versus INSURE technique.
Materials and methods: A detailed history and examination, procedure was done under aseptic precaution. The MIST method includes tracheal catheterization, intrapharyngeal instillation, and aerosolization. In this study, we will use a 4 to 5 FG (French Gauge) gastric tube as a conduit for insertion into the airway.
Results: In our study, all neonates included were born preterm, with an average gestational age of 31.93 ± 2.57 weeks in the INSURE group and 32.07 ± 2.12 weeks in the MIST group. The mean APGAR scores at 1 minute and 5 minutes exhibited close similarity between both groups. Instances of early onset sepsis, necrotizing enterocolitis, intraventricular hemorrhage, and pulmonary hemorrhage were noted in some neonates within both study groups. Conclusion: Surfactant administration for premature infants is vital important to prevent mortality and complications secondary to RDS. Conventionally minimally invasive techniques have less complications when compared to invasive method. But in resource limited settings one can consider both techniques as it has similar outcome with noninvasive one.
References
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Dr Sushrutha K P
Assistant Professor, Department of Pediatrics, Chamrajnagar institute of Medical sciences, Chamarajanagara- 571313
Dr Mahanthesh P
Assistant Professor, Department of Dermatology,leprosy and venereology, Karwar institute of medical sciences, Karwar
Dr Lingaraju N
Assistant Professor, Department of ENT, Chamrajnagar institute of Medical sciences, Chamarajanagara- 571313
Dr Rohith C S
Assistant Professor, Department of Orthopedics, Chamrajnagar institute of Medical sciences, Chamarajanagara- 571313