ASSOCIATION OF PSORIASIS WITH CARDIOVASCULAR MORBIDITY DETECTED BY HEART RATE VARIABILITY
Main Article Content
Keywords
Abstract
Several studies have documented an increased prevalence of cardiovascular diseases in patients with severe psoriasis but not enough studies are there suggesting this association with mild and moderate psoriasis. Heart Rate Variability (HRV) is a noninvasive method to interpret the sympathetic-parasymthetic interplay on cardiovascular system (CVS). Our study indicated an increased sympathetic activity and decreased parasympathetic activity measured by HRV in moderate cutaneous psoriasis (Psoriasis Area Severity Index [PASI] score 5-10), in the absence of other cardiovascular morbidities. Since the increase in sympathetic and decrease in parasympathetic activity can be associated with increased risk for CVS morbidities, moderate cutaneous psoriasis can be considered as an independent risk factor for cardiovascular disorders.
References
2. Tobin AM, Veale DJ, Fitzgerald O, Rogers S, Collins P, O’Shea DO et al. Cardiovascular disease and risk factors in patients with psoriasis and psoriatic arthritis. The Journal of rheumatology. 2010 Jul; 37(7): 1386-94.
3. Abboud FM, Harwani SC, Chapleau MW. Autonomic neural regulation of the immune system: implications for hypertension and cardiovascular disease. Hypertension. 2012; 59(4): 755-762.
4. Grassi G, Cattaneo BM, Seravalle G, Lanfranchi A, Mancia G. Baroreflex control of sympathetic nerve activity in essential and secondary hypertension. Hypertension. 1998; 31(1): 68-72.
5. Patil L, Jadhav A, Borade NG. A comparative study of heart rate variability during Valsalva maneuver in healthy, hypertensive and hypertensive diabetic subjects. IOSR Journal of Dental and Medical Sciences. 2013; 4(4): 29-32
6. Task Force of the European Society of Cardiology and North American Society of Pacing and Electrophysiology. Heart rate variability: Standards of measurement, physiological interpretation and clinical use. Circulation. 1996; 93:1043-1065.
7. Bicer A, Akdemir R, Karakurt O, Akis HK, Karasu B, Sezen Y et al. Heart rate variability and turbulence analysis in patients with psoriasis. Dicle Medical Journal 2010; 37(4): 326.
8. Proietti I, Raimondi G, Skroza N, Pampena R, Bernardini, N, La Viola G et al. Cardiovascular risk in psoriatic patients detected by heart rate variability (HRV) analysis. Drug development research. 2014; 75: S81-S84.
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Neha Aggarwal
VCSG Government Institute of Medical Sciences & Research, Srinagar Garhwal, Uttarakhand, India – 246174
Jai Kumar
VCSG Government Institute of Medical Sciences & Research, Srinagar Garhwal, Uttarakhand, India – 246174
Chander Shekhar
GMC Karauli, Bichpuri, Rajasthan-322241
Jyotsana Shukla
VCSG Government Institute of Medical Sciences & Research, Srinagar Garhwal, Uttarakhand, India – 246174