WHEN A SAVIOUR BECOMES THE CULPRIT: PREGABALIN-INDUCED NEUROTOXICITY IN AN ELDERLY PATIENT WITH DIABETIC KIDNEY DISEASE: A CASE REPORT IN CENTRAL INDIA
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Keywords
Pharmacovigilance, Pregabalin, Neurotoxicity, Chronic Kidney Disease, Diabetic Neuropathy, Haemodialysis, Drug Toxicity.
Abstract
Background: Pregabalin, a commonly prescribed medication for diabetic neuropathy, is primarily eliminated through renal excretion. In patients with chronic kidney disease (CKD), impaired renal clearance can result in drug accumulation and neurotoxicity. This article reports a case of pregabalin-induced neurotoxicity in an elderly patient with diabetic kidney disease, highlighting the importance of dose adjustment and the role of haemodialysis in managing toxicity.
References
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Healy DG, Ingle GT, Brown P. Pregabalin- and gabapentin-associated myoclonus in a patient with chronic renal failure. Mov Disord. 2009;24:2028–2029.
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