COMPARING ROLE OF USG AND CT SCAN IMAGING IN BILIARY TRACT MALIGNANCY
Main Article Content
Keywords
Biliary tract, gall bladder, cholangiocarcinoma, CT, USG, peri-ampullary region.
Abstract
BACKGROUND
- Biliary tract cancer ranks as the second most common hepatobiliary malignancy after hepatocellular carcinoma.
- The entire biliary tree, including the gallbladder, is lined with simple columnar epithelium. When this epithelium undergoes malignant transformation, it most commonly results in adenocarcinomas.
- Clinical history, geographic background, risk factors, patient’s age and gender are often crucial for arriving at diagnosis of these tumors.
- Multimodality imaging plays a deep and integral role in the management of malignancies of the biliary tract.
MATERIAL AND METHODS
- This study involved 50 patients with suspected biliary tract malignancy, conducted from January 2024 to September 2024. The study group consisted of mainly patients from different parts of Gujarat, neighbouring states of Rajasthan and Madhya Pradesh.
- The research was carried out in the Department of Radiology at Gujarat Cancer Research Hospital and BJ Medical College in Asarva, Ahmedabad.
RESULTS:
- In my study, gallbladder cancer was found to be more prevalent (52%) than cholangiocarcinoma (26%) and periampullary carcinoma (22%) among all types of biliary tract malignancies.
- In my study, mass replacing gall bladder (11 patients, 42%) and gall bladder wall thickening(13patients, 50%)wereequallyprevalentingall bladdertumors.
- periductal infiltrating type was found to be the most common radiological feature of hilar cholangiocarcinoma on both USG and CT.
- In my study, all patients exhibited a dilated common bile duct and main pancreatic duct, known as the double duct sign. Periampullary lesions, either as intraluminal masses or wall thickening, were visualized in 73% (8 out of 11) of the patients.
CONCLUSION
- USG scored slightly better over CT in cases of mild wall thickenings of gall bladder for detecting and differentiating them from benign gall bladder wall lesions. However,CTwas more sensitive in detection of infiltration of lesions in adjacent liver.
- Among hilar and extrahepatic cholangiocarcinoma, USG was less sensitive than CT for detection of primary tumor.For detection of biliary tract dilatation, USG and CT were equally sensitive.
- CT was highly sensitive in detecting metastatic lesions in different regions of body.
References
1. Cleary SP, Dawson LA, Knox JJ, Gallinger S: Cancer of the gallbladder and extrahepatic bile ducts. Curr ProblSurg 2007, 44:396–482.
2. Craig JR, Peters RL, Edmondson HA: Tumors of the liver and intrahepatic bileducts.InAtlasofTumorPathology.2ndseries.Fascicle26.Washington, D.C: Armed Forces Institute of Pathology; 1989
3. MukhopadhyayS,LandasSK:Putativeprecursorsofgallbladderdysplasia:a review of 400 routinely resected specimens. Arch Pathol Lab Med 2005, 129:386–390.
4. AdsayNV,KlimstraDS:Benignandmalignanttumorsofthegallbladderand extrahepatic biliary tree. In Surgical pathology of the GI tract, liver, biliary tract and pancreas. 2nd edition. Edited by Odze RD, Goldblum JR. Philadelphia, PA: Saunders Elsevier; 2009:845–875
5. Katabi N: Neoplasia of gallbladder and biliary epithelium. Arch Pathol Lab Med 2010, 134:1621–1627.
6. Razumilava N, Gores GJ: Classification, diagnosis, and management of cholangiocarcinoma. Clin Gastroenterol Hepatol 2013, 11:13–21.
7. Heinrich S, Clavien PA: Ampullary cancer. Curr Opin Gastroenterol 2010, 26(3):280–285.
8. Van Leeuwen DJ, Fockens P. Tumors of the extrahepatic biliary tract and gallbladder. In: Brandt LJ, editor. Clinical practice of gastroenterology. Philadelphia: Churchill Livingstone; 1999. p. 1122–32.
9. Levy AD, Murkata LA, Rohrmann CA. Gallbladder carcinoma: radiologic– pathologic correlation. Radiographics 2001; 21:295–314.
10. LimJH.Cholangiocarcinoma:morphologicclassificationaccordingtogrowth pattern and imaging findings. Am J Roentgenol 2003; 181:819–27.
2. Craig JR, Peters RL, Edmondson HA: Tumors of the liver and intrahepatic bileducts.InAtlasofTumorPathology.2ndseries.Fascicle26.Washington, D.C: Armed Forces Institute of Pathology; 1989
3. MukhopadhyayS,LandasSK:Putativeprecursorsofgallbladderdysplasia:a review of 400 routinely resected specimens. Arch Pathol Lab Med 2005, 129:386–390.
4. AdsayNV,KlimstraDS:Benignandmalignanttumorsofthegallbladderand extrahepatic biliary tree. In Surgical pathology of the GI tract, liver, biliary tract and pancreas. 2nd edition. Edited by Odze RD, Goldblum JR. Philadelphia, PA: Saunders Elsevier; 2009:845–875
5. Katabi N: Neoplasia of gallbladder and biliary epithelium. Arch Pathol Lab Med 2010, 134:1621–1627.
6. Razumilava N, Gores GJ: Classification, diagnosis, and management of cholangiocarcinoma. Clin Gastroenterol Hepatol 2013, 11:13–21.
7. Heinrich S, Clavien PA: Ampullary cancer. Curr Opin Gastroenterol 2010, 26(3):280–285.
8. Van Leeuwen DJ, Fockens P. Tumors of the extrahepatic biliary tract and gallbladder. In: Brandt LJ, editor. Clinical practice of gastroenterology. Philadelphia: Churchill Livingstone; 1999. p. 1122–32.
9. Levy AD, Murkata LA, Rohrmann CA. Gallbladder carcinoma: radiologic– pathologic correlation. Radiographics 2001; 21:295–314.
10. LimJH.Cholangiocarcinoma:morphologicclassificationaccordingtogrowth pattern and imaging findings. Am J Roentgenol 2003; 181:819–27.
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Published
Jan 17, 2025
Article Details
How to Cite
Dr. Saumil Desai, Dr.Sapna Patel, Dr.Alpesh Kalsaria, & Dr.Tarun Kumar. (2025). COMPARING ROLE OF USG AND CT SCAN IMAGING IN BILIARY TRACT MALIGNANCY. Journal of Population Therapeutics and Clinical Pharmacology, 32(1), 212-220. https://doi.org/10.53555/nxh34138
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Author Biographies
Dr. Saumil Desai
Associate Professor,Gujarat cancer & research Institute, Gujarat, India
Dr.Sapna Patel
Associate Professor, Gujarat cancer & research institute, Gujarat, India
Dr.Alpesh Kalsaria
3rd year Resident, 2nd year Resident, Gujarat cancer & research institute, India
Dr.Tarun Kumar
3rd year Resident, 2nd year Resident, Gujarat cancer & research institute, India
How to Cite
Dr. Saumil Desai, Dr.Sapna Patel, Dr.Alpesh Kalsaria, & Dr.Tarun Kumar. (2025). COMPARING ROLE OF USG AND CT SCAN IMAGING IN BILIARY TRACT MALIGNANCY. Journal of Population Therapeutics and Clinical Pharmacology, 32(1), 212-220. https://doi.org/10.53555/nxh34138