THE POWERHOUSES OF THE ENDOCRINE SYSTEM: THYROID, PITUITARY, AND ADRENAL GLANDS
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Keywords
Endocrine system, thyroid gland, pituitary gland, adrenal glands, hormones, metabolism, homeostasis, hormonal balance, endocrine disorders, diagnostic methods, treatment methods
Abstract
Background: The endocrine system is a network of glands that produce hormones, which are chemical messengers released into the bloodstream to regulate various bodily functions. Key glands in this system include the thyroid, pituitary, and adrenal glands, often referred to as the "powerhouses" of the endocrine system.
Objective: This article aims to discuss the anatomical structure and functioning of the thyroid, pituitary, and adrenal glands, highlighting their essential roles in maintaining hormonal balance. Additionally, it explores common disorders associated with each gland and current diagnostic and treatment methods.
Methods: A comprehensive review of existing literature from PubMed and other reputable sources was conducted to compile information on the structure, function, and clinical significance of the thyroid, pituitary, and adrenal glands.
Results: Thyroid Gland: Located in the neck, the thyroid gland produces hormones that control metabolism, growth, and development. These hormones regulate the function of most cells and organs in the body.
Pituitary Gland: Known as the "master gland," the pituitary is located at the base of the brain and controls other endocrine glands, such as the thyroid and adrenal glands, by secreting stimulating hormones.
Adrenal Glands: Situated atop the kidneys, the adrenal glands produce hormones like cortisol and adrenaline, which are crucial for stress management and maintaining homeostasis.
Conclusion: Understanding the interconnected roles and hormonal interactions between the thyroid, pituitary, and adrenal glands is vital for comprehending their collective impact on the endocrine system. This review underscores the significance of these glands in human physiology and disease control by providing an extensive summary of their individual and combined functions, common disorders, and current diagnostic and treatment approaches.
References
2. HATHI, D., et al., Association of COVID-19 and Endocrine Disorders. Journal of Clinical & Diagnostic Research, 2022. 16(2).
3. Wright, M., Secrets about Bioidentical Hormones to Lose Fat and Prevent Cancer, Heart Disease, Menopause, and Andropause, by Optimizing Adrenals, Thyroid, Estrogen. 2010: Lulu. com.
4. Taïeb, D. and K. Pacak, Current Diagnostic and Therapeutic Approaches in Nuclear Endocrinology. 2021: Cambridge Scholars Publishing.
5. Dorow, S.A. and G. Northrop, Thyroid and Parathyroid Diseases and Pain. Pain management: a practical guide for clinicians, 2002: p. 91.
6. Giampapa, V.C., Every man takes the limits of his field of vision for the limits of the world. The Principles and Practice of Antiaging Medicine for the Clinical Physician, 2022.
7. Edwards, C., ACADEMIA’S NEW bEDFEllOW? Molecular medicine, 2013. 16(P17): p. P16.
8. Shames, R., K. Shames, and G.G. Shames, Thyroid Mind Power: The Proven Cure for Hormone-Related Depression, Anxiety, and Memory Loss. 2011: Rodale Books.
9. SAJOUS, C.E.D.M., TISSUE RESPIRATION, UNEXPLAINED SINCE THE DISCOVERY OF OXYGEN, AS THE FUNDAMENTAL FUNCTION OF THE ENDOCRINES, AND ITS MEANING IN PRACTICAL MEDICINE. Transactions of the American Therapeutic Society, 1928: p. 154.
10. Dean, C., Hormone Balance: A Woman's Guide to Restoring Health and Vitality. 2005: Simon and Schuster.
11. REDMON, G.L., Oxytocin: Bodybuilding’s Most Misunderstood Anabolic Hormone.
12. Midzak, A. and V. Papadopoulos, Adrenal mitochondria and steroidogenesis: from individual proteins to functional protein assemblies. Frontiers in endocrinology, 2016. 7: p. 106.
13. Bagmut, I.Y., et al., Condition of the hormonal status of the body in white rats under the exposure to sodium fluoride. Проблеми екології та медицини, 2019(23,№ 3-4): p. 22-25.
14. Phalkey, R., et al., Human physiology, hazards, and health risks, in Clay's Handbook of Environmental Health. 2022, Routledge. p. 337-458.
15. MacKendrick, N.A. and H. Troxel, Like a finely-oiled machine: Self-help and the elusive goal of hormone balance. Social Science & Medicine, 2022. 309: p. 115242.
16. Feyz, M., et al., Effect of protein levels and rumen-protected glutamine supplementation on blood metabolites, thyroid hormones, and redox status of heat stressed fattening lambs. Iranian Journal of Applied Animal Science, 2021. 11(3): p. 557-565.
17. Salas-Lucia, F. and A.C. Bianco, T3 levels and thyroid hormone signalling. Frontiers in Endocrinology, 2022. 13: p. 1044691.
18. Vitti, A., Womancode: Perfect Your Cycle, Amplify Your Fertility, Supercharge Your Sex Drive and Become a Power Source. 2013: Hay House, Inc.
19. Bhattacharya, A., et al., Neuroendocrine and cellular mechanisms in stress resilience: From hormonal influence in the CNS to mitochondrial dysfunction and oxidative stress. Journal of Cellular and Molecular Medicine, 2024. 28(7): p. e18220.
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Praveenkumar Periyasamy
Lecturer, Department of Anatomy, Levy Mwanawasa Medical University, Lusaka, Zambia
Arike Badaru
MD, Department of Medicine, New Vision University, Tbilisi, Georgia
Krisli Serani
Anesthesia and Reanimation Specialist, Anaesthesia and Intensive Care Unit, University of Medicine Tirana Albania/ Memorial Hospital Fier Albania, Albania
Tariq Rafique
Assistant Professor Dadabhoy Institute of Higher Education, Karachi, Pakistan,