A NEW APPROACH TO RESTORATIVE DENTISTRY USING PEPTIDE-ENHANCED DENTAL CEMENTS FOR STRONGER BONDS
Main Article Content
Keywords
.
Abstract
Dental materials make drastic impacts on the success rate and durability of all the restorative procedures. More recently, the development of dental cements containing bioactive peptides has been considered as a prospect for increasing the adhesive properties to dentin and enamel. This paper examines the synthesis and functionalization of dental cements with incorporation of peptides, and its performance characteristics such as mechanical properties, biocompatibility and adhesion as compared to the conventional cements. Studies done in a test tube have postulated that using peptides in cement increases bond strength and predictive of increasing the durability of restorations.
References
2. Burke FJ, Fleming GJ, Owen FJ, Watson DJ. Materials for restoration of primary teeth: 2. Glass ionomer derivatives and compomers. Dent Update [Internet]. 2002 [cited 2024 Sep 18];29(1). Available from: https://pubmed.ncbi.nlm.nih.gov/11890017/
3. Muñoz MA, Luque I, Hass V, Reis A, Loguercio AD, Bombarda NHC. Immediate bonding properties of universal adhesives to dentine. J Dent. 2013 May;41(5):404–11.
4. Jefferies S. Bioactive and Biomimetic Restorative Materials: A Comprehensive Review. Part II. J Esthet Restor Dent [Internet]. 2014 Jan 1 [cited 2024 Sep 18];26(1):27–39. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/jerd.12066
5. Sideridou ID, Achilias DS, Karava O. Reactivity of Benzoyl Peroxide/Amine System as an Initiator for the Free Radical Polymerization of Dental and Orthopaedic Dimethacrylate Monomers: Effect of the Amine and Monomer Chemical Structure. Macromolecules. 2006 Mar 21;39(6):2072–80.
6. Montoya C, Roldan L, Yu M, Valliani S, Ta C, Yang M, et al. Smart dental materials for antimicrobial applications. Bioact Mater. 2023 Jun 1;24:1–19.
7. Nakabayashi N, Saimi Y. Bonding to Intact Dentin. http://dx.doi.org/101177/00220345960750091401 [Internet]. 1996 Sep 1 [cited 2024 Sep 18];75(9):1706–15. Available from: https://journals.sagepub.com/doi/10.1177/00220345960750091401
8. Hardan L, Chedid JCA, Bourgi R, Cuevas-Suárez CE, Lukomska-Szymanska M, Tosco V, et al. Peptides in Dentistry: A Scoping Review. Bioengineering [Internet]. 2023 Feb 1 [cited 2024 Sep 18];10(2). Available from: /pmc/articles/PMC9952573/
9. Akbarian M, Khani A, Eghbalpour S, Uversky VN. Bioactive Peptides: Synthesis, Sources, Applications, and Proposed Mechanisms of Action. Int J Mol Sci [Internet]. 2022 Feb 1 [cited 2024 Sep 18];23(3). Available from: https://pubmed.ncbi.nlm.nih.gov/35163367/
10. Ferracane JL, Sidhu SK, Melo MAS, Yeo ISL, Diogenes A, Darvell BW. Bioactive dental materials: Developing, promising, confusing. JADA Found Sci. 2023 Jan 1;2:100022.
11. Ostermann F, Meyer G, Kern M. Survey of clinically used adhesive ceramic bonding methods - follow up after 12 years. Dent Mater [Internet]. 2021 Apr 1 [cited 2024 Sep 18];37(4):e195–200. Available from: https://pubmed.ncbi.nlm.nih.gov/33334585/
12. Fröhlich TT, Gindri LD, Soares FZM, de Oliveira Rocha R. Does the etching strategy influence the bonding of universal adhesive systems to primary teeth? A systematic review and meta-analysis of in vitro studies. Eur Arch Paediatr Dent [Internet]. 2021 Dec 1 [cited 2024 Sep 18];22(6):1015–22. Available from: https://link.springer.com/article/10.1007/s40368-021-00639-w
13. Attar N, Tam LE, McComb D. Mechanical and physical properties of contemporary dental luting agents. J Prosthet Dent. 2003 Feb 1;89(2):127–34.
14. Du Z, Li Y. Review and perspective on bioactive peptides: A roadmap for research, development, and future opportunities. J Agric Food Res. 2022 Sep 1;9:100353.
15. Burke FJ, Watts DC. Fracture resistance of teeth restored with dentin-bonded crowns. Quintessence Int [Internet]. 1994 May 1 [cited 2024 Sep 18];25(5):335–40. Available from: https://europepmc.org/article/MED/7938418
16. Deb S, Chana S. Biomaterials in Relation to Dentistry. Front Oral Biol. 2015;17:1–12.
17. Universal adhesives: the evolution of adhesive solutions continues - PubMed [Internet]. [cited 2024 Sep 18]. Available from: https://pubmed.ncbi.nlm.nih.gov/25076499/
18. Bhandari D, Rafiq S, Gat Y, Gat P, Waghmare R, Kumar V. A Review on Bioactive Peptides: Physiological Functions, Bioavailability and Safety. Int J Pept Res Ther [Internet]. 2020 Mar 1 [cited 2024 Sep 18];26(1):139–50. Available from: https://link.springer.com/article/10.1007/s10989-019-09823-5
19. Perdigão J, Araujo E, Ramos RQ, Gomes G, Pizzolotto L. Adhesive dentistry: Current concepts and clinical considerations. J Esthet Restor Dent [Internet]. 2021 Jan 1 [cited 2024 Sep 18];33(1):51–68. Available from: https://onlinelibrary.wiley.com/doi/full/10.1111/jerd.12692
20. Perdigão J. Current perspectives on dental adhesion: (1) Dentin adhesion – not there yet. Jpn Dent Sci Rev [Internet]. 2020 Nov 1 [cited 2024 Sep 18];56(1):190. Available from: /pmc/articles/PMC8216299/
Article Sidebar
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
All articles published in JPTCP are licensed under Copyright Creative Commons Attribution-NonCommercial 4.0 International License.
Dr. Ali Hamad Khan
DS, M. Phil (Science of Dental Materials), Assistant Professor Dental Materials Frontier Medical & Dental College, Abbottabad Pakistan
Dr. Sajid Hussain
BDS, M. Phil (Science of Dental Materials), P.hD Scholar, Assistant Professor Dental Materials Sardar Begum Dental College, Peshawar Pakistan
Dr. Sadam Hussain
BS Dental Technology Iqra National University, Peshawar Pakistan
Dr. Sabahat Ullah
BDS, House Officer, Sardar Begum Dental College, Peshawar Pakistan
Dr. Asad Khan
BDS, M. Phil (Science of Dental Materials), Assistant Professor Dental Materials Sardar Begum Dental College, Peshawar Pakistan
Dr. Atta Elahi
BDS, M. Phil (Science of Dental Materials), Assistant Professor Dental Materials, Shahida Islam Medical & Dental College, Lodhran Pakistan