CAUSES OF MORTALITY IN HOSPITALIZED PCR POSITIVE PATIENTS OF COVID 19 IN TERTIARY CARE HOSPITAL
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Keywords
Covid 19, ARDS, mortality
Abstract
Objectives: To evaluate the causes of mortality in hospitalized PCR positive patients of Covid 19 in tertiary care hospital.
Materials and Methods: This retrospective observational study was conducted at Peshawar Medical College, Pakistan in the duration from November, 2023 to April, 2024. with ethical committee approval. We reviewed hospital records of 106 patients to collect demographic data, comorbidities, COVID-19 severity, treatment protocols, and causes of death. SPSS Version 25 was used for statistical analysis.
Results: We enrolled 106 patients with a mean age of 60.94 years. Among them, 43.4% were male and 56.6% were female. The majority were over 60 years old. Of the total, 77.4% survived while 22.6% died. ARDS and pneumonia were the most common causes of death, each accounting for 23.6% of cases. Sepsis caused 12.3% of deaths, cardiac arrest 4.7%, chronic pulmonary disease 6.6%, hypertension 17.9%, and diabetes mellitus 11.3%. The differences in ARDS, sepsis, cardiac arrest, pneumonia, chronic pulmonary disease, hypertension, and diabetes between deceased and surviving patients were not statistically significant.
Conclusion: It was concluded that ARDS and pneumonia were the main causes of mortality, each significantly affecting the death rate. Sepsis, cardiac arrest, and comorbidities like chronic pulmonary disease, hypertension, and diabetes also critically influenced patient outcomes. These findings underscore the need for effective management of respiratory complications and sepsis to improve survival. They also highlight the importance of monitoring and treating comorbidities to mitigate their impact on COVID-19 severity and mortality.
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Fida Hussain
Medical Officer, Health Department Balochistan, Pakistan
Arooba Arshad
Medicine Department, PNS Shifa Karachi, Pakistan
Humaira Niaz
Riphah University Peshawar Medical College, Pakistan
Zaghum Abbas
Post Graduate Resident, Quaid-e-Azam Medical College Bhawalpur, Pakistan
Sana Afzal
MBBS, Lahore Medical and Dental College, Lahore, Pakistan
Farah Ali
Senior House Officer, HepatoPancreaticoBiliary & Liver Transplant Unit, Shaikh Zayed Hospital Lahore, Pakistan