EFFECTIVENESS OF COORDINATIVE LOCOMOTOR TRAINING ON BALANCE AND GAIT IN CHEMOTHERAPY INDUCED PERIPHERAL NEUROPATHY PATIENTS

Main Article Content

Aqsa Liaqat
Dr. Anbreena Rasool
Rabeea Saeed
Nimra Amin
Ulvina
Ishal Ayub
Hifza Ahmed

Keywords

neuropathy, chemotherapy induced peripheral neuropathy, coordinative locomotor training, CLT, balance, gait

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is the term used to describe the peripheral neuropathy brought on by chemotherapy drugs. CIPN results in numbness, tingling sensation, balance and gait problems. Coordinative locomotor training (CLT) is a non-invasive treatment that combines the PNF patterns with sprinter/skater coordination. The goal of this study was to observe the effectiveness of Coordinative locomotor training on balance and gait in chemotherapy induced peripheral neuropathy patients. For this purpose, a single blinded randomized controlled trial with the sample size of 38 was conducted. After enrollment patients were randomly allocated into two groups. Group A was the interventional group in which participants received Coordinative locomotor training for 30 minutes per session. They were instructed to perform sprinter and skater patterns in three postures that were supine, sitting and half standing. In one session, a total of 3 sets (one set for each posture) with 10 repetitions of each sprinter and skater patterns were performed. While group B was the control group in which participants received conventional physical therapy for 30 minutes. Both interventions were applied three times per week for four weeks. Tinetti performance-oriented mobility assessment (POMA), Timed Up and Go (TUG) test and F8WT were used as outcome measures. Data was recorded at baseline and after applying the interventions for 4 weeks. For the analysis and comparing the recorded data SPSS version 23 was used.

Abstract 83 | PDF Downloads 26

References

1. Australia H. Cancer-Symptoms, Causes, Diagnosis And Treatments. 2023 Aug 12;25(56):256-98.
2. Aslam MS, Naveed S, Ahmed A, Abbas Z, Gull I, Athar Majjoct. Side Effects Of Chemotherapy In Cancer Patients And Evaluation Of Patients Opinion About Starvation Based Differential Chemotherapy. 2014 July 7;2014(5):6
3. Cavaletti Gjjotpns. Chemotherapy‐Induced Peripheral Neurotoxicity (CIPN): What We Need And What We Know. 2014 June 26;19(2):66-76.
4. Brown TJ, Sedhom R, Gupta Ajjo. Chemotherapy-Induced Peripheral Neuropathy. 2019 May 1;5(5):750.
5. Grisold W, Cavaletti G, Windebank AJJN-O. Peripheral Neuropathies From Chemotherapeutics And Targeted Agents: Diagnosis, Treatment, And Prevention. 2012 Sep 1;14(Suppl_4):Iv45-Iv54.
6. Kolb NA, Smith AG, Singleton JR, Beck SL, Stoddard GJ, Brown S, Et Al. The Association Of Chemotherapy-Induced Peripheral Neuropathy Symptoms And The Risk Of Falling. 2016 Jul 1;73(7):860-6.
7. Smith EML, Pang H, Cirrincione C, Fleishman S, Paskett ED, Ahles T, Et Al. Effect Of Duloxetine On Pain, Function, And Quality Of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial. 2013 Apr 3;309(13):1359-67.
8. Hershman DL, Lacchetti C, Dworkin RH, Lavoie Smith EM, Bleeker J, Cavaletti G, Et Al. Prevention And Management Of Chemotherapy-Induced Peripheral Neuropathy In Survivors Of Adult Cancers: American Society Of Clinical Oncology Clinical Practice Guideline. 2014 Jun 20;32(18):1941-67.
9. Oh P-J, Kim Yljjokaon. Effectiveness Of Non-Pharmacologic Interventions In Chemotherapy Induced Peripheral Neuropathy: A Systematic Review And Meta-Analysis. 2018 Apr 1;48(2):123-42.
10. Melese H, Alamer A, Hailu Temesgen M, Kahsay G. Effectiveness Of Exercise Therapy On Gait Function In Diabetic Peripheral Neuropathy Patients: A Systematic Review Of Randomized Controlled Trials. Diabetes, Metabolic Syndrome And Obesity. 2020 Aug 5;13(2020):2753-64.
11. Lim J-H, Lee M-K, Kim T-Y, Ko H-E. The Combination Of PNF Patterns For Coordinative Locomotor Training. PNF And Movement. 2013 Jun 30;11(1):17-25.
12. Kim J-C, Lim J-Hjjoer. The Effects Of Coordinative Locomotor Training On Coordination And Gait In Chronic Stroke Patients: A Randomized Controlled Pilot Trial. 2018 Dec 27;14(6):1010.
13. Kim J-C, Lim J-H. The Effects Of Coordinative Locomotor Training On Coordination And Gait In Chronic Stroke Patients: A Randomized Controlled Pilot Trial. Journal Of Exercise Rehabilitation. 2018 Dec 27;14(6):1010.
14. Ko H-E, Jeon B-S, Song H-SJP, Movement. Effects Of Coordinative Locomotor Training Program On Balance And Gait Of Stroke Patients. 2017 Dec 31;15(3):247-52.
15. Hwang J-K, Park J-S, Lim J-Hjjotksopm. Effects Of Coordinative Locomotor Training Program On Low Extremity Strength, Balance And Quality Of Life In Patients With Cancer: Single-Subject Design. 2017 Nov 30;12(4):47-59.
16. Andersen Hammond E, Pitz M, Steinfeld K, Lambert P, Shay B. An Exploratory Randomized Trial Of Physical Therapy For The Treatment Of Chemotherapy-Induced Peripheral Neuropathy. Neurorehabilitation And Neural Repair. 2020 Jan 24;34(3):235-46.
17. Bahar-Ozdemir Y, Akyuz G, Kalkandelen M, Yumuk Pfjajopm, Rehabilitation. The Effect Of Therapeutic Exercises On Balance, Quality Of Life, And Pain In Patients Who Were Receiving Neurotoxic Chemotherapy. 2020 Apr 1;99(4):291-9.
18. Seth NH, Quershi IJF. Effect Of Proprioceptive Neuromuscular Facilitation Technique And TENS On Improving Lower Limb Sensorimotor Function, Balance And Quality Of Life In Chemotherapy Induced Peripheral Neuropathy In Gynecological Cancer: A Randomized Controlled Trial Protocol. 2023 May 22;12:527.
19. Dhawan S, Andrews R, Kumar L, Wadhwa S, Shukla Gjcn. A Randomized Controlled Trial To Assess The Effectiveness Of Muscle Strengthening And Balancing Exercises On Chemotherapy-Induced Peripheral Neuropathic Pain And Quality Of Life Among Cancer Patients. 2020 Jul 1;43(4):269-80.
20. Ferrucci L, Koh C, Bandinelli S, Guralnik JM. Chapter 21 - Measuring Disability. In: Duthie EH, Katz PR, Malone ML, Editors. Practice Of Geriatrics (Fourth Edition). Philadelphia: W.B. Saunders; 2007. P. 255-70.
21. Kear BM, Guck TP, Mcgaha AL. Timed Up And Go (TUG) Test: Normative Reference Values For Ages 20 To 59 Years And Relationships With Physical And Mental Health Risk Factors. Journal Of Primary Care & Community Health. 2016 Jul 25;8(1):9-13.
22. Katirci Kirmaci ZI, Adiguzel H, Erel S, Inanç Y, Tuncel Berktas D. The Reliability And Validity Of The Figure Of 8 Walk Test In Mildly Disabled Persons With Multiple Sclerosis. Multiple Sclerosis And Related Disorders. 2023 Jan 1;69(9):104430.
23. Stubblefield MD, Burstein HJ, Burton AW, Custodio CM, Deng GE, Ho M, Et Al. NCCN Task Force Report: Management Of Neuropathy In Cancer. 2009 Sep 1;7(Suppl_5):S-1-S-26.
24. Bakitas Majnr. Background Noise: The Experience Of Chemotherapy-Induced Peripheral Neuropathy. 2007 Sep 1;56(5):323-31.
25. Tinetti Mejnejom. Preventing Falls In Elderly Persons. 2003 Jan 2;348(1):42-9.
26. Sharma V, Kaur J. Effect Of Core Strengthening With Pelvic Proprioceptive Neuromuscular Facilitation On Trunk, Balance, Gait, And Function In Chronic Stroke. Journal Of Exercise Rehabilitation. 2017 Apr 30;13(2):200-5.
27. Lim C-Gjtjokpt. The Effects Of Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercise Using The Sprinter And The Skater On Balance And Gait Function In The Stroke Patients. 2014 Aug 30;26(4):249-56.
28. Martinez JW, Sanchez-Naranjo JC, Londono-De Los Rios PA, Isaza-Mejia CA, Sosa-Urrea JD, Martinez-Munoz MA, Et Al. Prevalence Of Peripheral Neuropathy Associated With Chemotherapy In Four Oncology Centers Of Colombia. 2019 Aug 1;69(3):94-8.
29. Greenwald MK, Ruterbusch JJ, Beebe-Dimmer JL, Simon MS, Albrecht TL, Schwartz AG. Risk Of Incident Claims For Chemotherapy-Induced Peripheral Neuropathy Among Women With Breast Cancer In A Medicare Population. Cancer. 2019 Jan 15;125(2):269-77.
30. Molassiotis A, Cheng HL, Leung KT, Li YC, Wong KH, Au JSK, Et Al. Risk Factors For Chemotherapy‐Induced Peripheral Neuropathy In Patients Receiving Taxane‐And Platinum‐Based Chemotherapy. 2019 Jun 1;9(6):E01312.
31. Lee Hgjjokpts. The Effect Of Coordinative Locomotor Training Using Elastic Band On Pain, Muscle Strength, Dynamic Balance And Muscle Activity Of Female College Students With Patellofemoral Pain Syndrome. 2023 Sep 30;30(3):59-71.
32. Lee J-A, Kim J-Cjjotksopm. Effect Of Coordinative Locomotor Training On Postural Imbalance And Gait In Children: A Single Subject Design. 2019 Aug 31;14(3):63-71.

Most read articles by the same author(s)