DEVELOPMENT AND CHARACTERIZATION OF MICROSPONGE GEL CONTAINING PIPERINE FOR ANTI-BACTERIAL
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Keywords
Microsponges, Oral administration, Controlled release, Piperine, Antibacterial
Abstract
The polymeric system made up of porous microspheres that can entrap and release Microsponges into the skin over an extended length of time is the highly cross-linked, porous microsphere delivery system used in Microsponges. With less discomfort, increased tolerance, and enhanced thermal, physical, and chemical stability, this delivery technique offers longer release. Emulsion systems or suspension polymerization into a liquid-liquid system are two methods used to create Microsponges. Microsponges are capable of encasing different kinds of drugs and can be used in lotions, creams, powders, and gel formulations. Piperine is found in black pepper, white pepper and long pepper belonging to the family Piperaceae. Piperine represents diverse biological activities, such as anti-inflammatory, anticancer, antiviral, anti-larvicidal, pesticide, anti-Alzheimer’s, antidepressant and most importantly piperine is known as the bioavailability enhancer. The current review article aims to explore the Development and Characterization of Microsponge Gel Containing Piperine for Anti-Bacterial effect.
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Satbir Singh
Associate Professor, Pt. LR College of Pharmacy, Faridabad
Dr. M.K. Gupta
Dean and Principal, Career Point School of Pharmacy, Kota (Rajasthan)
Dr. Anjana Devi
Associate Professor, Department of Pharmacy, Career Point University, Hamirpur,H.P.