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Hina Tariq Jan
Lubna Aslam
Faiza Ali
Muniba Gul
Muhammad Haider Ali


Fibroids, pregnancy, fetal outcomes, maternal outcomes, abortions


Objective: To assess the prevalence and types of adverse pregnancy outcomes in patients with uterine fibroids at a tertiary care hospital.

Methods: This observational cohort study, conducted at the Department of Obstetrics and Gynecology, Hayatabad Medical Complex Peshawar, Pakistan over a six-month period from November 2023 to April, 2024, aimed to investigate pregnancy outcomes in women with ultrasonography (USG)-documented uterine fibroids. Eligible participants, aged 18 to 40 years, were pregnant women visiting the hospital, excluding those with adnexal pathologies, previous uterine surgery, or obstetrical comorbidities. Retrospective data collection from patient case files ensured confidentiality, covering demographic details, antenatal/intrapartum/postpartum history, clinical examinations, laboratory investigations, USG findings, and obstetric and neonatal outcomes. Statistical analysis utilized descriptive statistics and multiple logistic regression. Ethical considerations included obtaining informed consent, and approval from the Institutional Ethics Committee, ensuring data confidentiality and research integrity.

Results: In this study of 90 pregnant women with uterine fibroids, most were aged 25-32 years, with a significant proportion being primigravida and having a BMI >30. Sub-serous fibroids predominated, mainly located in the fundus. Cesarean section was common, primarily due to PROM and malpresentation. Complications included threatened preterm labor, blood transfusion, and threatened miscarriage. Fetal outcomes showed a high incidence of low birth weight, NICU admission, neonatal resuscitation, and low APGAR scores. Miscarriage, antepartum bleeding, and neonatal mortality were also observed.


Our study highlights the challenges posed by uterine fibroids during pregnancy, leading to increased risks of complications such as abortion, premature rupture of membranes, and postpartum hemorrhage. While cesarean sections are frequently required, our findings suggest that fibroid characteristics may not consistently predict maternal outcomes. This stresses the need for vigilant monitoring and tailored management strategies to optimize outcomes for both mothers and babies in this high-risk population.

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