ANALYTICAL CROSS-SECTIONAL STUDY TO DETERMINE WHETHER SIGNIFICANT CORRELATION IS PRESENT BETWEEN CORRECTED QT INTERVAL WITH BMI AND WAIST-HIP RATIO IN 1ST PROFESSIONAL MBBS STUDENTS IN MEDICAL TEACHING INSTITUTE
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Keywords
Corrected QT Interval, BMI, Waist-hip Ratio, MBBS students
Abstract
Prolonged QT interval is associated with high incidence of coronary heart disease in adults. Our country has a significant prevalence of coronary heart disease, and now the prevalence of obesity is also increasing specially among the younger population. Obesity is also found to be associated with prolonged QT interval. This study was carried out to determine whether significant correlation is present between QTc (corrected QT interval) and waist-hip ratio and BMI in 1st professional MBBS students. This is a cross-sectional (observational), analytical study. BMI, waist & hip circumference and ECG are recorded by standard techniques. Waist hip ratio (WHR) is calculated. QTc is calculated using Bazett’s formula. Pearson’s correlation coefficient will be calculated for association between BMI and QTc as well as for association between WHR and QTc. This study shows that QTc interval in young adults is significantly positively correlated with BMI, WC, and WHR. Obesity is associated with increase in levels of leptin, free fatty acids and pro-inflammatory cytokines. The findings of this study will motivate the population towards a life of enhanced physical activity
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Bhausaheb Jagdale
Associate Professor, Department of Physiology, SMBT Institute of Medical Sciences and Research Centre, Dhamangaon, Nashik, Maharashtra, India
Priyanka Mourya
Assistant Professor, Department of Physiology, SMBT Institute of Medical Sciences and Research Centre, Dhamangaon, Nashik, Maharashtra, India
Yash chandak
Tutor, Department of Endocrinology, TNMC & BYL Nair Hospital, Mumbai, Maharashtra, India.
Ameya Degloorkar
Medical Officer, Sub-district Hospital Kalamnuri, Nanded, Maharashtra, India.
Vrushabh Daga
Osteopathic Medical Student III (OMS-III), University of New England College of Osteopathic Medicine, Biddeford Maine, United States
Prafulla Chandak
Professor, Department of Physiology, SMBT Institute of Medical Sciences and Research Centre, Dhamangaon, Nashik, Maharashtra, India