Predictors of Periprocedural Myocardial Injury Following Elective PCI

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Khaled Elsayed Hamada , Mohammed Kamal Salama, Wael Anwar Haseeb, Reda Biomy Bastawisy


MACEs, All-Cause Death, Periprocedural Myocardial Injury& PCI.


Periprocedsural myocardial injury is associated with major adverse cardiovascular events (MACE) after percutaneous coronary intervention (PCI). The aim of this work was to evaluate the predictors of periprocedural myocardial injury following elective PCI.

Methods: This prospective observational cohort study was carried out on 300 adult cases of both sexes who were diagnosed with chronic coronary syndromes (CCS) and were treated by elective PCI and had normal baseline levels of high sensitivity cardiac troponin I (hs-cTnI). Patients were categorized into two groups according to the post-PCI hs-cTnI level: no post-PCI myocardial injury group with hs-cTnI level (<99th percentile URL) and post-PCI myocardial injury group with elevation of hs-cTnI level > 99th percentile URL.

Results: The multivariate regression analysis illustrated that the age, stent number and total stent length were independent predictors of myocardial injury, while EF, lesion complexity, syntax score, PCI vessels number and average stent diameter were not. CV death, cardiac arrest, MI, MACEs and all cause death were significantly higher in group II than group I.

Conclusions: In CCS patients undergoing elective PCI, age, stent number and total stent length were independent predictors of myocardial injury. Myocardial injury with higher hs-cTnI level > 99th percentile URL was associated with higher risk of CV death, cardiac arrest, MI, MACEs and all cause death.

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