Main Article Content

Dr. Ali Qaisar
Dr. Amber Fatima
Dr. Naveed Hussain
Dr. Mahnoor Khan Jamali
Dr. Sohaib Hassan
Dr. Abdul Aziz
Dr. Areesha Arkan
Dr. Hamad Bin Rashid


Thrush, Horse hoof, Treatment, Pythium oligandrum, Healing observations



Horse thrush is a frequent ailment that affects the frog of the foot and, if left untreated, can result in disability. Using eighteen afflicted horses, this study evaluated three treatments: Pythium oligandrum (Ecosin), magnesium sulfate and thrush powder, Complete blood count (CBC), lameness score, and hoof clinical examination were components of the evaluation. Treatment impact analysis was done using GLM and One-way ANOVA. When compared to magnesium sulfate and thrush powder, ecosin shown a significant (P < 0.05) improvement in healing duration and lameness score. With the exception of platelets (P = 0.004) that preferred Ecosin over magnesium sulfate, CBC values did not differ substantially (P > 0.05) between treatments. In comparison to the other therapies, Ecosin showed early infection removal and faster thrush healing overall.


Abstract 58 | pdf Downloads 34


1. Abidina NSZ, Adamua L, Ahmada B. 2013. Incidence of equine hoof derangements in Malaysian horse population. IOSR J. Agric. Vet. Sci. 5(2): 26-32.
2. Agne B. 2010. Diagnosis and treatment of foot infections. J. Equine Vet. Science. 30(9): 510-512. Aiello SE, Moses MA, Allen DG. 2016. The Merck veterinary manual.11th Ed, Merck & Company, Incorporated. Philadelphia, USA. p.1117-1118.
3. Al-Agele R, Paul E, Dvojmoc VK, Sturrock CJ, Rauch C, Rutland CS. 2019. The anatomy, histology and physiology of the healthy and lame equine hoof. Vet. Anat. Physiol. 13: 19- 56.
4. Anonymous. 2019-20. Economic survey of Pakistan. Government of Pakistan, Islamabad, Pakistan. p. 17-41.
5. Azargoon H, Williams BJ, Solomon ES, Kessler HP, He J, Spears R. 2011. Assessment of hemostatic efficacy and osseous wound healing using HemCon dental dressing. J. Endo. 37(6): 807-811.
6. Back W, Clayton H.M. 2013. Equine locomotion. 2nd Ed, Elsevier Health Sciences, London, UK. p. 31-66.
7. Bassage LH, Ross MW, Dyson SJ. 2011. The antebrachium. Diagnosis and Management of Lameness in the Horse. p. 449-455.
8. Benhamou N, Le Floch G, Vallance J, Gerbore J, Grizard D, Rey P. 2012. Pythium oligandrum: an example of opportunistic success. Microbiol. 158(11) : 2679-2694.
9. Daniel WW, Cross CL. 2018. Biostatistics: a foundation for analysis in the health sciences. 11th Ed. USA: John Wiley & Sons. p. 173-177,267-340.
10. Fisahaye T, Tesfaye R, Yihdego H. 2018. A study on hoof abnormalities among working donkeys presented to veterinary clinics in and around Mekelle, Ethiopia. Ethiop. Vet. J. 22(1): 111- 120.
11. Floyd A, Mansmann R. 2007. Equine Podiatry-E-Book. Elsevier Health Sciences, London, UK. p.393-396.
12. Gabrielova A, Mencl K, Suchanek M, Klimes R, Hubka V, Kolarik M. 2018. The oomycete Pythium oligandrum can suppress and kill the causative agents of dermatophytoses. Mycopathologia. 183(5): 751-764.
13. Holzhauer M, Bremer R, Santman-Berends I, Smink O, Janssens I, Back W. 2017. Cross-sectional study of the prevalence of and risk factors for hoof disorders in horses in the Netherlands. Prev. Vet. Med. 140: 53-59.
14. Kiros A, Gezahegn M, Aylate A. 2016. A cross sectional study on risk factors associated with lameness of working donkeys in and around Hawassa, Ethiopia. J. Anim. Health Prod. 4(3): 87-94.
15. Kumar S, Dedar R, Singh J, Manuja A. 2014. Treatment of hoof thrush with triple sulphate in Farriers a pony. Onl. J. Vet. Res. 18: 511-515.
16. Laskoski LM, Sousa RS. 2015. Histopathological hoof laminar changes in horses with Pituitary Pars Intermedia Adenoma: cases report Veterinary Medicine. Arq. Bras. Med. Vet. Zootec. 67 (5): 1226-1230.
17. Lundeberg R, Leach J, Garrett A, Evenson D, Pehling P, Stark C, Thiel E. 2017. The Horse's Health. p. 41-43.
18. Morison AE. 1918. The treatment of infected war wounds by magnesium sulphate. Brit. Med. J.1(2986): 342.
19. Načeradská M, Fridrichová M, Kellnerová D, Peková S, Lány P. 2017. Antifungal effects of the biological agent Pythium oligandrum observed in vitro. J. Feline Med. Surg. 19(8): 817- 823.
20. Načeradská M, Fridrichová M, Kolářová MF, Krejčová T. 2021. Novel approach of dermatophytosis eradication in shelters: effect of Pythium oligandrum on Microsporum canis in FIV or FeLV positive cats. BMC Vet. Res. 17(1): 1-10.
21. O'Grady SE. 2018. Equine Thrush: A Closer Look. Am. J. 44(8): 1-4.
22. Petrov KK, Dicks LM. 2013. Fusobacterium necrophorum, and not Dichelobacter nodosus, is associated with equine hoof thrush. Vet. Microbiol. 161(3-4): 350-352.
23. Pollard D, Wylie CE, Verheyen KLP, Newton JR. 2019. Identification of modifiable factors associated with owner-reported equine laminitis in Britain using a web-based cohort study approach. BMC Vet. Res. 15(1): 59.
24. Popescu S, Diugan E A. 2013. The relationship between behavioral and other welfare indicators of working horses. J. Equine Vet. Sci. 33(1): 1-12.
25. Rashid H B, Khan M S, Chaudhry M, Khan M A, & Ashraf M. 2018. Effects of different combinations of acepromazine, detomidine, xylazine and ketamine on serum cortisol level of standing sedated horses. J. Anim. Plant Sci. 28(3): 960-964.
26. Reeves MJ, Yovich JV, Turner AS. 1989. Miscellaneous conditions of the equine foot. Vet. Clin. North Am: Equine Pract. 5(1): 221-242.
27. Sanjay K, Ramesh D, Jitender S, Anju M. 2014. Treatment of hoof thrush with triple sulphate in a pony. Onl. J. Vet. Res. 18(6): 511-515.
28. Sen CK, Khanna S, Venojarvi M, Trikha P, Ellison EC, Hunt TK, Roy S. 2002. Copper-induced vascular endothelial growth factor expression and wound healing. Am. J. Physiol. Heart Circ.282(5): 1821-1827.
29. Shin S-K, Kim S-M, Lioyd S, Cho G-J. 2020. Prevalence of hoof disorders in horses in South Korea. Open Agric. J. 14(1): 25-29.
30. Stashak TS. 2013. Adam's Lameness in Horses. 6th Ed, Lea & Febiger, Philadelphia, USA. p. 540- 541.
31. Stoltz JA. 2018. Literature review of three common equine hoof ailments. J. Undergrad. St. Trent.6(1): 17-23.
32. Tadesse D, Asefa Z, Alemu A, Endebu B, Kassaye A, Fanta A, Chaburte C. 2019. Identification of causes and associated risk factors for lameness in working donkeys in and around Bishoftu. J. Anim. Sci. Vet. Med. 4(1): 16-23.
33. Turner T A. 2003. Examination of the equine foot. Vet. Clin: Equine Prac. 19(2): 309-332.
34. Viñuela-Fernández I, Jones E, Chase-Topping M E, Price J. 2011. Comparison of subjective scoring systems used to evaluate equine laminitis. Vet. J. 188(2): 171-177.
35. Voelker R. 2000. Copper and Cancer. J. Am. Med. Assoc. 283(8): 994-994.