RECURRENT ODONTOGENIC KERATOCYST. A CASE REPORT
Main Article Content
Keywords
Odontogenic keratocysts, (OKCs), benign cystic lesions, Cone Beam CT
Abstract
Odontogenic keratocysts (OKCs) are benign cystic lesions originating from the dental lamina remnants, predominantly localized in the mandible's ramus and posterior body. Despite their benign nature, OKCs pose diagnostic and management challenges due to their potential for rapid growth and high recurrence rates. In this report, we present a case study of a 25-year-old male patient in whom a well-defined radiolucency with sclerotic borders was incidentally detected during pantomogram imaging. Subsequent histological examination and biopsy of the cyst wall revealed characteristic features consistent with mandibular body OKC, characterized by a cyst lined with parakeratinized stratified squamous epithelium. This case highlights the importance of meticulous radiographic assessment and histopathological analysis for accurate diagnosis and appropriate management of OKCs. Our findings contribute to the understanding and clinical management of this challenging entity in oral pathology.
References
2. Madhireddy MR, Prakash AJ, Mahanthi V, Chalapathi KV. Large follicular odontogenic keratocyst affecting maxillary sinus mimicking dentigerous cyst in an 8-year-old boy: a case report and review. International Journal of Clinical Pediatric Dentistry. 2018 Jul;11(4):349.
3. Peraza A, González L, González N. Outcome after 8 years of a modified conservative treatment experience in keratocystic odontogenic tumor in 5 patients. Oral and Maxillofacial Surgery Cases. 2017 Jun 1;3(2):42-7.
4. Valdivia AD, Ramos-Ibarra ML, Franco-Barrera MJ, Arias-Ruiz LF, García-Cruz JM, Torres-Bugarín O. What is currently known about odontogenic keratocysts. Oral Health Prev Dent. 2022 Jun 1;20(1):321-30.
5. Forssell K, Sorvari TE, Oksala E. A clinical and radiographic study of odontogenic keratocysts in jaws. Proceedings of the Finnish Dental Society. Suomen Hammaslaakariseuran toimituksia. 1974 Aug;70(4):121-34.
6. Chi AC, Owings Jr JR, Muller S. Peripheral odontogenic keratocyst: report of two cases and review of the literature. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 2005 Jan 1;99(1):71-8.
7. Kaczmarzyk T, Stypułkowska J, Tomaszewska R. Update of the WHO classification of odontogenic and maxillofacial bone tumours. Journal of Stomatology. 2017;70(5):484-506.
8. Miyamoto S, Goto T, Shirakawa J, Kawano T, Murahashi M, Ide K, Maruyama N, Matayoshi A, Nishihara K, Nakamura H. Odontogenic keratocyst in the mandibular condyle base region: A case report. Experimental and Therapeutic Medicine. 2023 Mar 1;25(3):1-6.
9. Kshirsagar RA, Bhende RC, Raut PH, Mahajan V, Tapadiya VJ, Singh V. Odontogenic keratocyst: Developing a protocol for surgical intervention. Annals of maxillofacial surgery. 2019 Jan 1;9(1):152-7.
10. Menon S. Keratocystic odontogenic tumours: etiology, pathogenesis and treatment revisited. Journal of maxillofacial and oral surgery. 2015 Sep;14:541-7.
11. Jaeger F, de Noronha MS, Silva ML, Amaral MB, Grossmann SD, Horta MC, de Souza PE, de Aguiar MC, Mesquita RA. Prevalence profile of odontogenic cysts and tumors on Brazilian sample after the reclassification of odontogenic keratocyst. Journal of Cranio-Maxillofacial Surgery. 2017 Feb 1;45(2):267-70.
12. Franchi A, Skalova A. Undifferentiated and dedifferentiated head and neck carcinomas. InSeminars in Diagnostic Pathology 2021 Nov 1 (Vol. 38, No. 6, pp. 127-136). WB Saunders.
13. Kadashetti V, Patil N, Datkhile K, Kanetakar S, Shivakumar KM. Analysis of expression of p53, p63 and proliferating cell nuclear antigen proteins in odontogenic keratocyst: An immunohistochemical study. Journal of Oral and Maxillofacial Pathology. 2020 May 1;24(2):273-8.