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Dr. Rizwan Afzal
Prof. Dr Syed Nurul Haque


Intravenous Dexmedetomidine, Intrathecal Spinal Anesthesia, Incidence of shivering, Sedation level


This study aimed to assess the effectiveness of dexmedetomidine in preventing shivering during spinal anesthesia. A total of 377 patients aged 18 to 50 were registered for elective minor surgical procedures under bupivacaine spinal anesthesia. The study divided the patients into two groups: those receiving intravenous dexmedetomidine (DEX) and those receiving saline (Placebo). The Bromage Scale was used to evaluate motor block, and an observer blinded to the situation evaluated if shivering occurred following a subarachnoid medication injection loaded with cerebrospinal fluid.

The results showed that shivering occurred in 14% of the DEX group and 28% in the placebo group. The DEX group experienced less severe shivering than the Placebo group. The duration between the initiation of shivering in the DEX group and the placebo group was 30 and 82 minutes, respectively. Additionally, 78% of the DEX group and 3% of the placebo group experienced sedation at level 2.

In conclusion, dexmedetomidine infusion significantly reduced shivering during the perioperative period due to its quick start of action, higher cessation rates, and decreased recurrence. These findings highlight the safety and effectiveness of adding dexmedetomidine to anesthesia protocols to improve patient outcomes and offer insights for anesthesiologists and other healthcare professionals.

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