EVALUATION OF COMPARATIVE WOUND HEALING EFFICACY OF ALOE VERA AND ACACIA HONEY ALONE AND IN COMBINATION ON BURN WOUNDS IN RABBIT MODEL
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Keywords
H2SO4, parchment paper, Acacia honey, Aloe vera, silver sulfadiazine
Abstract
Burn injuries are a complex and painful condition that pose many challenges. To reduce tissue scarring and avoid infection, wounds must be managed effectively. While honey is prized for its analgesic, hemostatic, anti-inflammatory, antimicrobial, and wound-healing qualities, aloe vera is known for its wide range of pharmaceutical and therapeutic qualities. The purpose of this study was to assess the effects of honey and aloe vera, both separately and together, on the healing of burn wounds. From local sources, forty healthy adult rabbits of different sexes were acquired and appropriately acclimated. The animals were split into four groups after being given burn wounds to the thoracolumbar region. Group B was treated with honey, and Group A was treated with aloe vera. Group D was given silver sulfadiazine as the control, while Group C was given a mixture of honey and Aloe vera. Tensile strength, healing time, contraction rate, and histopathological analysis of the regenerated tissue were among the metrics used to assess the effectiveness of the healing process. The statistical analysis employed ANOVA, and the mean differences were assessed using the least significant difference (LSD) test. The findings show that aloe vera and acacia honey together significantly increased wound contraction rate and tensile strength, which in turn shortened the healing period. Therefore, it is confidently advised to combine aloe vera and acacia honey for efficient wound healing in both humans and animals.
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This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
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Nadeem Raza
Department of Veterinary Medicine, University of Veterinary and Animal Sciences, Lahore, Pakistan.
Absar Ahmad
Para-Veterinary Institute, Karor Lal-Eason (Sub Campus) University of Veterinary and Animal Sciences, Lahore, Pakistan
Muhammad Rizwan
Multan College of Veterinary Sciences, Multan University of Science and Technology Multan, Pakistan
Hafiz Muhammad Usman Abid
Department of Pharmaceutics, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan
Abdul Aziz
Department of Veterinary Clinical Sciences, University of Poonch, Rawalakot, Pakistan