OUTCOMES OF NEPHRECTOMY APPROACHES: OPEN VS. LAPAROSCOPIC IN 156 PATIENTS A CROSS SESSIONAL STUDY

Main Article Content

Sadaqat Ali Khan
Akhtar Nawaz
Muhammad Saad Hamid
Siddiq Akbar
Muhammad Waqas

Keywords

Nephrectomy, Laparoscopic, Open, Outcomes

Abstract

Objectives


This study compares the outcomes of laparoscopic and open nephrectomy procedures at the Institute of Kidney Diseases, Hayatabad, focusing on operative details, complications, and patient outcomes.


Study Design: A Cross sessional study


Duration and Place of Study: Conducted between 05-March 2020 and 05-March 2021 at the Institute of Kidney Diseases, Hayatabad Peshawar, Pakistan


Materials and Methods


In this Cross sessional study, we analysis of 156 nephrectomy cases was performed between 05-March 2020 and 05-March 2021 at the Institute of Kidney Diseases, Hayatabad. Data on patient demographics, operative details, complications, and outcomes were collected from medical records. Statistical analysis was performed using SPSS Version 22, with comparisons made between laparoscopic and open nephrectomy groups. Chi-Square test and Student's t-test were utilized, with a significance level set at p < 0.005.


Results


The study included 156 nephrectomy cases, with 80 undergoing open nephrectomy and 76 laparoscopic nephrectomy. Laparoscopic nephrectomy demonstrated several advantages over open nephrectomy, including shorter operative time (125.4 vs. 145.2 minutes), reduced blood loss (54.75 vs. 359.24 ml), lower transfusion rates (11.04% vs. 52%), fewer postoperative complications (20.4% vs. 51.4%), shorter hospital stays (02.6 vs. 03.8 days), and superior pain control (06.8% vs. 96.4%). Additionally, laparoscopic nephrectomy resulted in smaller incisions and better cosmesis. No intraoperative complications were reported in the laparoscopic group, compared to two cases of minor inferior vena cava injury in the open group. The mean tumor size was smaller in the laparoscopic group (05.43 cm vs. 08.2 cm). Overall, laparoscopic nephrectomy demonstrated superior perioperative and postoperative outcomes compared to open nephrectomy, indicating its potential as the preferred approach for nephrectomy procedures.


Conclusion


Laparoscopic nephrectomy emerges as the preferred approach due to superior perioperative and postoperative postoperative outcomes compared to open nephrectomy. Increased training in laparoscopic surgery is recommended to align with global trends favoring minimally invasive techniques in nephrectomy procedures.

Abstract 20 | Pdf Downloads 4

References

1. Gill IS, Kavoussi LR, Lane BR, et al. Comparison of 1,800 laparoscopic and open partial nephrectomies for single renal tumors. J Urol. 2007;178(1):41-46.
2. Fergany AF, Hafez KS, Novick AC. Long-term results of nephron sparing surgery for localized renal cell carcinoma: 10-year followup. J Urol. 2000;163(2):442-445.
3. Clayman RV, Kavoussi LR, Soper NJ. Laparoscopic nephrectomy. N Eng J Med 1991; 324: 1370-1371.
4. Binsaleh S, Alomar M, Madbouly K. Pfannenstiel incision for intact specimen extraction in laparoscopic transperitoneal radical nephrectomy: a longitudinal prospective outcome study. CLINICS 2015;70(7):475-480.
5. Sanli O, Tefik T, Ortac M, Karadeniz M, Oktar T, Nane I, Tunc M. Laparoscopic Nephrectomy in Patients Undergoing Hemodialysis Treatment. JSLS 2010;14:534-540.
6. Skrekas G, Papalois VE, Mitsis M, Hakim NS. Laparoscopic Live Donor Nephrectomy: A Step Forward in Kidney Transplantation? JSLS 2003;7:197-206.
7. Jain S, Saltzman, Miller A, Ortiz J, Nofziger J. Same-Day Discharge for Laparoscopic Donor Nephrectomy. JSLS 2017;21(2) e2017.00019
8. Mahesan N, Choudhury SM, Khan MS, Murphy DG, Dasgupta P. One hand is better than two: conversion from pure laparoscopic to the hand-assisted approach during difficult nephrectomy. Ann R Coll Surg Engl 32011;93:229-231.
9. Silberstein J, Parsons K. Hand-Assisted and Total Laparoscopic Nephrectomy: a Comparison. JSLS 2009;13:36-43.
10. Dirie NI, Wang Q, Wang S. Two-Dimentional Versus Three-Dimentional Laparoscopic Systems in Urology: A Systematic Review and Meta-Analysis. JOURNAL OF ENDOUROLOGY 2018;32(9):781-790.
11. Eskicorapci SE, Teber D, Schulze M, Ates M, Stock C, Rassweiler JJ. Laparoscopic Radical Nephrectomy: The New Gold Standard Surgical Treatment for Localized Renal Cell Carcinoma. TSW Urology 2007;2:99-110.
12. Yang F, Zhou Q, Li X, Xing N. The methods and techniques of identifying renal pedicle vessels during retroperitoneal laparoscopic radical and partial nephrectomy. World Journal of Surgical Oncology 2019;17:38.
13. Lee H, Lee CU, Yoo JH, et al. Comparison of oncological outcomes and perioperative complications between laparoscopic and open radical nephrectomies in patients with clinical T2 renal cell carcinoma(≥7cm). PLoS ONE 13(1):e0191786.
(http://doi.org/10.1371/journal.pone.0191786)
14. Rosoff JS, Raman JD, Sosa RE, Del Pizzo JJ. Laparoscopic Radical Nephrectomy for Renal Masses 7 Centimeters or Larger. JSLS 2009;13:148-153.
15. Xu H, Ding Q, Jiang H. Fewer complications after laparoscopic nephrectomy as compared to the open procedure with the modified Clavien classification system retrospective analysis from Southern China. World Journal of Surgical Oncology. 2014;12:242.
(http://www.wjso.com/content/12/1/242)
16. Reifsnyder JE, Ramasamy R, Shariat SF. Laparoscopic and Open Partial Nephrectomy: Complication Comparison Using the Clavien System. JSLS 2012;16:38-44.
17. Ma L, Yu Y, Ge G, Li G. laparoscopic nephrectomy outside rota fascia and en bloc ligation of the renal hilum for management of inflammatory renal diseases. IBJU 2018;44(2):280-287.
18. Parker PA, Swartz R, Fellman B, Urbauer D, Li Y, Pisters LL, Rosser CJ, Wood CG, Matin SF. Comprehensive Assessment of Quality of Life and Psychosocial Adjustment in Patients with Renal Tumours Undergoing Open, Laparoscopic and Nephron-Sparing Surgery. J Urol 2012;187(3):. doi:10.1016/j.juro.2011.10.151.
19. Abdelhafez M, Bastian A, Rausch S, Stenzl A, Bedke J, Kruck S. Laparoscopic versus open partial nephrectomy: comparison of overall and subgroup outcomes. Anticancer research. 2017 Jan 1;37(1):261-5.
20. Ng AM, Shah PH, Kavoussi LR. Laparoscopic partial nephrectomy: A narrative review and comparison with open and robotic partial nephrectomy. Journal of endourology. 2017 Oct 1;31(10):976-84.
21. Kızılay F, Turna B, Apaydın E, Semerci B. Comparison of long‐term outcomes of laparoscopic and robot‐assisted laparoscopic partial nephrectomy. The Kaohsiung journal of medical sciences. 2019 Apr;35(4):238-43.