INCIDENCE OF NON-INVASIVE VENTILATION FAILURE AND MORTALITY IN CHILDREN WITH ACUTE RESPIRATORY DISTRESS SYNDROME
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Abstract
Introduction: Acute respiratory distress syndrome (ARDS) poses a significant challenge in pediatric care due to its potential for respiratory failure and mortality.
Objectives: The main objective of the study is to find the incidence of non-invasive ventilation failure and mortality in children with acute respiratory distress syndrome.
Material and methods: This retrospective study was conducted at Lady Reading Hospital Peshawar from August 2020-August 2021. Data was collected from 220 patients suffering from ARDS.Patients meeting the inclusion criteria were identified, and their demographic information, clinical characteristics, and management details were extracted. Relevant data points included age, gender, comorbidities, etiology of ARDS, severity of illness scores, Pediatric Index of Mortality 2 - PIM2, oxygenation parameters, initiation and duration of non-invasive ventilation (NIV), complications during NIV therapy, outcomes and length of PICU stay.
Results: Data were collected from 220 patients from both genders suffering from ARDS. In the NIV success group, the mean age was 7.5± 2.1 years compared to 8.3± 2.5 years in the NIV failure group. The mean weight was slightly lower in the success group (24.5 kg ± 4.2) compared to the failure group (25.1 kg ± 4.5). Regarding ARDS severity, the majority of patients in both groups had moderate ARDS, with 46.2% and 44.4% in the success and failure groups, respectively. Among patients with mild ARDS, 10% experienced NIV failure, while in the moderate group, the failure rate increased to 25%. Significantly, patients with severe ARDS had the highest NIV failure rate at 40%.
Conclusion: It is concluded that non-invasive ventilation (NIV) failure rates differ significantly among children with acute respiratory distress syndrome (ARDS), with higher rates observed in severe ARDS cases.
References
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Dr Aamir Shehzad
District Children Specialist Department of Pediatrics Category D Hospital Totakan Batkhela, Malakand
Dr Osama Omer
Medical Officer Emergency Department Arif Memorial Teaching Hospital Lahore
Dr Arham Mahmood
Medical Officer Internal Medicine Arif Memorial Teaching Hospital Lahore
Ikram Ullah Khan
Department of Pediatric Saidu Group of Teaching Hospital, Swat
Ihsan Ullah Khan
District Children Specialist Paediatric Department MRHSM Hospital Pabbi, Nowshera
Dr Rabia Tabassum
Consultant Paediatrics Bilal Hospital Rawalpindi
Zara Haseen
Respiratory Therapist Darul Sehat Hospital Karachi
Dr. Hooria Ahmad
University College of Medicine and Dentistry, UOL Lahore