DECIPHERING THE DENGUE ENIGMA: UNRAVELING CLINICAL, HEMATOLOGICAL, AND SEROLOGICAL SIGNATURES IN RAWALPINDI, PAKISTAN

Abstract

Dengue virus produce by the bite of the mosquito. This virus is RNA single stranded. Severe illness has the symptoms of headache, fever, joint pain and rashes. Drinking fluid can help to cure from this disease so, Recovery generally takes two to seven days. This study was carried out at District Head Quarters hospitals which is located in Punjab province, Pakistan through the duration since July 2021 to Dec 2021. Those patients who visit the DHQ hospital will be enrolled as cases while con. A cross sectional study comprised of 166 dengue patients. All the subjects were enrolled on January 2022 at District Head Quarters hospital located in Punjab province, Pakistan. Data was analyzed on SPSS IBM version22.Continuous variables are normalized by mean and standard deviation, while categorical variables are described by frequency distribution and graph pad prism help us to find the percentage of IgG, IgM and NS1. In our research we took age, Diagnoses, IgM, IgG, HCT, PLT and TLC. Some patients through suffering from dengue fever continue to develop dengue hemorrhagic fever so in our diagnoses research we have 44.2% of DHF the study of dengue virus was divided into positive and negative according to NS1, IgM and IgG. In case of NS1 we have high rate of positive value (44.8%) and low rate of negative value (6.4%). In IgG we have 80.12% negative value and 19.88% positive value. In IgM we have 40.36% positive and 59.64% negative value. In descriptive analysis of PLT mean value is 59.29, HCT mean is 39.32 and TLC mean is 79.04. The significant of correlation of PLT and HCT is 0.05. To identify the disease, we use new molecular techniques. It has offered a fresh possibility for primary identification, even though they remain incomplete due to their expenses and standards. The use of antiviral drug medicines to cure this virus fever is still being investigated.