OVARIAN TUMORS: INCIDENCE AND SPECTRUM OF VARIOUS HISTOPATHOLOGICAL TYPES IN TERTIARY CARE HOSPITAL
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Keywords
Ovarian tumor, Incidence, Tertiary-care hospital, Malignancies
Abstract
Objective: To determine the incidence of ovarian tumors and to assess the spectrum of various histopathological types in tertiary care hospital.
Study Design: Retrospective study
Place and Duration of Study: Department of Histopathology, Services Institute of Medical Sciences, Lahore from 1st January 2023 to 31st December 2023.
Methodology: One hundred and five ovarian masses which were either part of abdominal-hysterectomy specimens or solitary specimens. Histopathological requisition forms were also filled out by every study participant. Different numbers of sections were taken from cysts and solid tumors. Sectioned-tissues were then processed and paraffin blocks were made from them. 5mm tissue sections were then taken and stained with eosin and hematoxylin. Morphologic features of tumors were recorded for histopathological diagnosis and classification of tumors.
Results: The mean age of the patients was 49.5±5.6 years with the highest number of malignancy cases within the age of 31-45 years. The histopathological slides presented various tumors with 30.47% (n=32) as malignant, with 37.14% (n=39) cases presenting tumor metastasis. There were 27.6% (n=29) cases having benign tumor types.
Conclusion: Most of the ovarian tumors observed in this study originated primarily from the ovary with a high number of malignant tumors. The majority of the tumors were surface epithelial
References
2. Sawant A, Mahajan S. Histopathological Study of Ovarian Lesions at a Tertiary Health Care Institute. MVP J Med Sci 2017; 4(1): 26–9.
3. Padubidri VG, Daftery SN. Disorders of ovary. In: Howkins & Bourne. Shaw’s. Textbook of Gynecology. 13th ed. Churchill Livingston, London; 2004, 352-485.
4. Basu P, De P, Mandal S, Ray K, Biswas J. Study of ‘patterns of care’ of ovarian cancer patients in a specialized cancer institute in Kolkatta, eastern India. Indian J Cancer 2009; 46(1): 28–33.
5. Mondal SK, Banyopadhyay R, Nag DR, Roychowdhury S, Mondal PK, Sinha SK. Histologic pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10-year study in a tertiary hospital of eastern India. J Can Res Ther 2011; 7: 433–7.
6. Berek JS, Thomas GM, Ozols RF. Ovarian Cancer. Practical gynecologic oncology, 3rd ed. Baltimore, MD: Lippincott Williams & Wilkins; 2000.
7. Schiff M, Becker TM, Smith HO, et al. Ovarian cancer incidence and mortality in American Indian, Hispanic, and non-Hispanic white women in New Mexico. Cancer Epidemiology, Biomarkers & Prevention, 1996; 5(5): 323-7.
8. Singh S, Saxena V, Khatri S, et al. Histopathological Evaluation of Ovarian Tumors. Imperial J Interdisciplinary Res 2016; 2(4): 435-9.
9. Thakkar N, Shah S. Histopathological Study of Ovarian Lesions. Int J Sci Res 2015; 4(10): 1745-9.
10. Bhattacharya MM, Shinde SD, Purrandare VN. A clinicopathological analysis of 270 ovarian tumors. J Postgrad Med 1980; 26: 103-7.
11. Agrawal P, Kulkarni DG, Cahkrabarti PR, et al. Clinicopathological Spectrum of Ovarian Tumors: A 5‑Year Experience in a Tertiary Health Care Center. Journal of Basic and Clinical Reproductive Sciences, 2015; 4(2): 90-96.
12. Couto F, Nadkarni NS, Rebello MJ. Ovarian Tumours in Goa-A clinicopathological study. Journal of Obstetrics and Gynaecology of India, 1993; 43(3): 408- 12.
13. Maheshwari V, Tyagi SP, Saxena K. Surface epithelial tumors of ovary. Indian J Pathol Microbiol., 1994; 37(10): 75 -85.
14. Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumours: a study of 282 cases. J Indian Med Assoc 2002; 100(7): 420-4.
15. Gupta. N, Bisht. D. Retrospective and prospective study of ovarian tumors and tumor like lesions. Indian J Pathol Microbiol 2007; 50(30): 525-7.
16. Badge SA, Sulhyan KR, Gosavi AV. Histopathological Study of Ovarian Tumors. Indian Medical Gazette 2013; 147(9): 345-51.
17. Wills V, et al. A study on clinico histopathological patterns of ovarian tumors. Int J Reprod Contracept Obstet Gynecol 2016; 5(8): 2666-71.
18. Mankar DV, Jain GK. Histopathological profile of ovarian tumours: A twelve year institutional experience. Muller J Med Sci Res 2015; 6(2): 107-11.
19. Malli M, Vyas B, Gupta S, Desai H. A histological study of ovarian tumors in different age groups. Int J Med Sci Public Health 2014; 3: 338-41.
20. Prabhakar BR, Maingi K. Ovarian tumours-prevalence in Punjab. Indian J Pathol Microbiol 1989; 32: 276-81.
21. Prakash A, Chinthakindi S, Duraiswami R, Indira V. Histopathological study of ovarian lesions in a tertiary care center in Hyderabad, India-a retrospective fiveyear study. Int J Adv Med 2017; 4: 745- 9.
22. Misra RK, Sharma SP, Gupta U, Gaur R, Misra SD. Pattern of ovarian neoplasm in eastern UP. J Obstet Gynaecol 1990; 41(2): 242-6.
23. Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J 2008; 10: 81-5.
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Saima Gulzar
Assistant Professor, Department of Histopathology, Services Institute of Medical Sciences, Lahore – Pakistan
Farida Kakar
Professor & Head of Obstetrics & Gynaecology, Unit-4, BMCH Bolan Medical College, Quetta - Pakistan
Amna Kazi
Associate Professor, Department of Obstetrics & Gynaecology, Shaikh Zayed Hospital, Lahore - Pakistan
Dilawar Sultan
Assistant Professor, Department of Operative Dentistry, Akhtar Saeed Medical & Dental College, Lahore - Pakistan