The Predictive Value of Red Blood Cell Distribution width (RDW) in Critically ill Children . A Cross sectional study

Main Article Content

Amr Ahmed Othman, Rezk Atalla Massoud, Al Zahraa El Sayed Ahmed, Shaimaa Mohammed Mahmoud

Keywords

RDW, ill children , PICU, severity scores.

Abstract

The objective of the study was evaluating the role  of RDW as  an indicator for severity of the illness in  diseased children with a critical condition


Patients and methods:  This cross-sectional hospital-based study included 111 children, 55 males (49.5 %).   . All diseased  children with critical condition met the following requirements were included in the research   , 2 month to 14 years old age, whose  were admitted to  the PICU, at Sohag University Hospital, during a period of 6 months, from the date of protocol acceptance, the following laboratory tests were performed to the patients during their stay ; Complete Blood Count, Serum electrolytes, Liver functions , kidney functions, CRP, Blood gases, Serum lactate, Coagulation profile, serum fibrinogen, and Blood urea nitrogen (BUN)   . All the followings were demonstrated,  the  need of patients for mechanical ventilation or for inotropes ,  the  hospital stay peroid and the outcome patients. Critical illness scores were calculated including, pediatric sequential organ failure assessment (PSOFA), pediatric logistic organ dysfunction-2 (PELOD-2). pediatric multiple organ dysfunction syndrome (PMODS) and  the pediatric risk of mortality (PRISM)


 


Results: In the study  participants  there was a  negative correlation between RDW level and the period of stay at PICU with a statistical significance  with p-value= 0.005  and also show a  positive correlation between RDW level and serum lactate and CRP  levels with a statistical significance with(p-value <0.007 and<0.006) respectively .There was a significant association between elevated RDW >16.9  with mortality rate among patients  and  R DW level had a  positive correlation with the prognostic severity  scores , which had previously been mentioned with a statistical significance  with ( p-value <0.008 ,  p-value<0.005 , p-value<0.005 and p-value <0.007  ) .


Conclusion:  RDW is a  non-invasive and simple easily applicable  marker and   it can be used as an additional prognostic factor and  a good predictor for  illness severity among critically ill children as it has a significant correlation  with the  prognostic severity scores

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