The Predictive Value of Red Blood Cell Distribution width (RDW) in Critically ill Children . A Cross sectional study
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Keywords
RDW, ill children , PICU, severity scores.
Abstract
The objective of the study was evaluating the role of RDW as an indicator for severity of the illness in diseased children with a critical condition
Patients and methods: This cross-sectional hospital-based study included 111 children, 55 males (49.5 %). . All diseased children with critical condition met the following requirements were included in the research , 2 month to 14 years old age, whose were admitted to the PICU, at Sohag University Hospital, during a period of 6 months, from the date of protocol acceptance, the following laboratory tests were performed to the patients during their stay ; Complete Blood Count, Serum electrolytes, Liver functions , kidney functions, CRP, Blood gases, Serum lactate, Coagulation profile, serum fibrinogen, and Blood urea nitrogen (BUN) . All the followings were demonstrated, the need of patients for mechanical ventilation or for inotropes , the hospital stay peroid and the outcome patients. Critical illness scores were calculated including, pediatric sequential organ failure assessment (PSOFA), pediatric logistic organ dysfunction-2 (PELOD-2). pediatric multiple organ dysfunction syndrome (PMODS) and the pediatric risk of mortality (PRISM)
Results: In the study participants there was a negative correlation between RDW level and the period of stay at PICU with a statistical significance with p-value= 0.005 and also show a positive correlation between RDW level and serum lactate and CRP levels with a statistical significance with(p-value <0.007 and<0.006) respectively .There was a significant association between elevated RDW >16.9 with mortality rate among patients and R DW level had a positive correlation with the prognostic severity scores , which had previously been mentioned with a statistical significance with ( p-value <0.008 , p-value<0.005 , p-value<0.005 and p-value <0.007 ) .
Conclusion: RDW is a non-invasive and simple easily applicable marker and it can be used as an additional prognostic factor and a good predictor for illness severity among critically ill children as it has a significant correlation with the prognostic severity scores
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